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Case Reports
. 2025 Jul 5;17(7):e87355.
doi: 10.7759/cureus.87355. eCollection 2025 Jul.

Laparoscopic Resection of a Cecal Schwannoma Presenting With Intussusception After a Seven-Year Follow-Up: A Case Report

Toru Takahashi  1 , Kimihiko Ueno  2 , Maria Takeda  2
Affiliations
Case Reports

Laparoscopic Resection of a Cecal Schwannoma Presenting With Intussusception After a Seven-Year Follow-Up: A Case Report

Toru Takahashi et al. Cureus. .

Abstract

An 88-year-old woman was diagnosed with a submucosal tumor of the cecum during a lower gastrointestinal endoscopy performed seven years earlier and had since been under regular follow-up. In August 2021, she began experiencing left-sided abdominal pain and bloating. A computed tomography (CT) scan conducted in September revealed a target sign in the ascending colon, with the tumor identified as the lead point of intussusception. She was referred to our department, where laparoscopic ileocecal resection was performed in November. Histopathological examination confirmed the diagnosis of schwannoma. Primary schwannomas of the colon are extremely rare, and cases originating in the cecum are particularly uncommon. We herein report a rare case of laparoscopically resected cecal schwannoma that developed intussusception after a prolonged follow-up period.

Keywords: case report; cecal schwannoma; colonic schwannoma; intussusception; laparoscopic resection.

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Conflict of interest statement

Human subjects: Informed consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. Abdominal contrast-enhanced CT findings at presentation.
Axial (A) and coronal (B) slice CT scans of the abdomen show that a 41-mm soft tissue mass with mild enhancement is seen in the cecum (arrow), located at the level of the inferior hepatic margin. A concentric ring appearance (target sign) is visible in the ascending colon, consistent with intussusception, with the tumor as the lead point.
Figure 2
Figure 2. Abdominal plain CT findings obtained seven years earlier.
Axial (A) and coronal (B) slice CT scans of the abdomen show that a known 3-cm submucosal mass is observed at the ileocecal region (arrow). No target sign is present at that time.
Figure 3
Figure 3. Pathological findings of the resected specimen.
(A) Macroscopic image showing a Type 1 tumor measuring 48 × 42 mm in the cecum. (B) Hematoxylin and eosin (H&E) staining demonstrates dense proliferation of spindle- and oval-shaped cells in the submucosa.
Figure 4
Figure 4. Pathological findings of the resected specimen.
Immunohistochemical staining shows strong positivity for vimentin (A) and S-100 protein (B).
Figure 5
Figure 5. Pathological findings of the resected specimen.
Negative staining for CD34 (A) and CD117/c-kit (B), supporting the diagnosis of schwannoma.
See this image and copyright information in PMC

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