Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Aug 7:27:e68348.
doi: 10.2196/68348.

Virtual Reality for Pediatric Postoperative Pain Management: Exploring Methods and Efficacy

Affiliations

Virtual Reality for Pediatric Postoperative Pain Management: Exploring Methods and Efficacy

Sidhant Kalsotra et al. J Med Internet Res. .

Abstract

Ineffective postoperative pain management affects more than 25% of hospitalized children, leading to increased morbidity, impaired physical function, delayed recovery, prolonged opioid use, and heightened health care costs. Traditional pharmacological interventions have limitations, particularly given growing concerns over long-term opioid use in pediatric populations. Virtual reality (VR) has emerged as a promising nonpharmacological intervention for pediatric pain management, offering immersive, multisensory experiences that can effectively distract and engage patients' attention away from pain sensations. This viewpoint examines the current evidence and prospects for VR as a component of pediatric multimodal pain management strategies. Several VR modalities have shown potential for reducing pain and anxiety in pediatric populations, including virtual reality-distraction therapy, virtual reality-exposure therapy, virtual reality-guided relaxation-based therapy, and virtual reality-biofeedback therapy. The neurobiological underpinnings of VR's analgesic effects involve multiple mechanisms: the gate control theory explains how intense multisensory VR inputs compete with pain signal transmission, while the attention-modulation pathways involving the anterior cingulate cortex and periaqueductal gray work alongside emotional regulation pathways through amygdala connections to reduce pain perception. Recent studies involving various pediatric surgical populations have demonstrated VR's potential to reduce postoperative pain intensity, pain unpleasantness, anxiety, and in some cases, the need for rescue analgesia. However, VR's analgesic effects appear to be transient, typically lasting 15-30 minutes, which suggests the need for optimization in timing and frequency of VR sessions. Implementation challenges include cost considerations, technological access disparities, logistical requirements for safe use and storage, and staff training needs. As hospitals and health care systems continue to explore nonpharmacological pain management strategies, VR represents a promising adjunct to traditional approaches, potentially reducing reliance on opioid medications while improving patient experience and outcomes. Throughout this viewpoint, we address the major concepts related to VR, the use of VR in differing clinical situations, various VR-based therapy methods, and the practicality of VR to alleviate pain, as well as several key findings to date and future directions.

Keywords: analgesia; pain management; pediatrics; post-operative; virtual reality.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: None declared.

References

    1. Forgeron PA, Finley GA, Arnaout M. Pediatric pain prevalence and parents’ attitudes at a cancer hospital in Jordan. J Pain Symptom Manage. 2006 May;31(5):440–448. doi: 10.1016/j.jpainsymman.2005.09.003. doi. Medline. - DOI - PubMed
    1. Taylor EM, Boyer K, Campbell FA. Pain in hospitalized children: a prospective cross-sectional survey of pain prevalence, intensity, assessment and management in a Canadian pediatric teaching hospital. Pain Res Manag. 2008;13(1):25–32. doi: 10.1155/2008/478102. doi. Medline. - DOI - PMC - PubMed
    1. Cummings EA, Reid GJ, Finley AG, McGrath PJ, Ritchie JA. Prevalence and source of pain in pediatric inpatients. Pain. 1996 Nov;68(1):25–31. doi: 10.1016/S0304-3959(96)03163-6. doi. Medline. - DOI - PubMed
    1. Gan TJ. Poorly controlled postoperative pain: prevalence, consequences, and prevention. J Pain Res. 2017;10:2287–2298. doi: 10.2147/JPR.S144066. doi. Medline. - DOI - PMC - PubMed
    1. Kozlowski LJ, Kost-Byerly S, Colantuoni E, et al. Pain prevalence, intensity, assessment and management in a hospitalized pediatric population. Pain Manag Nurs. 2014 Mar;15(1):22–35. doi: 10.1016/j.pmn.2012.04.003. doi. - DOI - PubMed