Acetylcholinesterase inhibition by eserine: rate constants of reaction. Part II
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Acetylcholinesterase inhibition by eserine: rate constants of reaction. Part II
Ital J Biochem.
1985 Sep-Oct.
Abstract
The inhibition of eel acetylcholinesterase by physostigmine at 20 degrees and 25 degrees C have been investigated. In our evaluation the unimolecular reactivation rate constant, k3, the carbamylation rate constant, k2, and the binding constant, Ka, are the first simultaneously determined. The mechanism of this reaction is discussed.
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