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. 2025 Aug 8.
doi: 10.1002/mds.70003. Online ahead of print.

Probabilistic Mapping of Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) Thalamotomy Targets in Essential Tremor and Tremor-Dominant Parkinson's Disease: Insights from a German Cohort

Jonas Krauss  1   2 , Neeraj Upadhyay  1 , Veronika Purrer  2   3 , Valeri Borger  4 , Marcel Daamen  1 , Hannah Weiland  1 , Angelika Maurer  1 , Carsten Schmeel  5 , Alexander Radbruch  3   5 , Markus Essler  1 , Ullrich Wüllner  2   3 , Henning Boecker  1   3
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Probabilistic Mapping of Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) Thalamotomy Targets in Essential Tremor and Tremor-Dominant Parkinson's Disease: Insights from a German Cohort

Jonas Krauss et al. Mov Disord. .

Abstract

Precise targeting in magnetic resonance-guided focused ultrasound (MRgFUS) is critical for effective tremor control in essential tremor and tremor-dominant Parkinson's disease, as small deviations can reduce efficacy or cause side effects. In our cohort, sweetspots were identified at Montreal Neurological Institute (MNI) coordinates x = -12.4, y = -17.5, z = -1.7 (ET) and x = -13.4, y = -19.8, z = -3.0 (TDPD).

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