A qualitative study on barriers and facilitators of COVID-19 vaccination during pregnancy among pregnant women in Malaysia
- PMID: 40779546
- PMCID: PMC12333975
- DOI: 10.1371/journal.pone.0329895
A qualitative study on barriers and facilitators of COVID-19 vaccination during pregnancy among pregnant women in Malaysia
Abstract
Background: COVID-19 vaccination is crucial for pregnant women to protect against severe complications during pregnancy. However, vaccine hesitancy and refusal can affect acceptance rates among this vulnerable group, posing risks to both maternal and fetal health. This research was conducted to explore the barriers and facilitators influencing COVID-19 vaccination among Malaysian pregnant women.
Methods: This qualitative study adopted a hermeneutic phenomenological design. Nineteen pregnant women receiving antenatal care at three clinics in Kelantan between February 2024 and June 2024 were purposively selected to participate in in-depth interviews. The interviews were audio-recorded, transcribed verbatim, and analyzed using NVivo software alongside manual coding. Thematic analysis, incorporating both inductive and deductive approaches, was conducted to identify key themes.
Results: Most pregnant women expressed hesitancy toward COVID-19 vaccination during pregnancy due to various concerns. Our findings identified four key themes as barriers to vaccination: (i) Fear of side effects, (ii) Negative social influences, (iii) Perception of returning to normalcy, and (iv) Vaccine scepticism and prejudice. Conversely, three themes emerged as facilitators of vaccine acceptance: (i) Concerns about the effects of COVID-19 infection, (ii) Trust in the vaccine, and (iii) Personal and shared vaccination experiences.
Conclusion: This study identified key factors influencing COVID-19 vaccine hesitancy. These findings highlight the importance of addressing both personal and social dimensions of vaccine hesitancy. Public health interventions should focus on building trust, countering misinformation, and leveraging positive community experiences to encourage vaccine uptake, particularly in populations where hesitancy remains a concern.
Copyright: © 2025 Mohamed Pauzi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Conflict of interest statement
The authors have declared that no competing interests exist.
Similar articles
-
Barriers and facilitators of COVID-19 vaccination among drug users: a qualitative analysis for future crisis management.BMC Infect Dis. 2025 Jul 11;25(1):909. doi: 10.1186/s12879-025-11248-z. BMC Infect Dis. 2025. PMID: 40646453 Free PMC article.
-
Examining the hesitations of pregnant women towards COVID-19 vaccines during the pandemic: A mixed methods approach.Midwifery. 2025 Sep;148:104469. doi: 10.1016/j.midw.2025.104469. Epub 2025 May 23. Midwifery. 2025. PMID: 40449311
-
COVID-19 vaccine barriers among pregnant and lactating refugee women: a case study.Front Public Health. 2025 Jul 8;13:1600107. doi: 10.3389/fpubh.2025.1600107. eCollection 2025. Front Public Health. 2025. PMID: 40697842 Free PMC article.
-
Factors that influence caregivers' and adolescents' views and practices regarding human papillomavirus (HPV) vaccination for adolescents: a qualitative evidence synthesis.Cochrane Database Syst Rev. 2025 Apr 15;4(4):CD013430. doi: 10.1002/14651858.CD013430.pub2. Cochrane Database Syst Rev. 2025. PMID: 40232221 Free PMC article.
-
Acceptance-Hesitancy of COVID-19 Vaccination and Factors Affecting It in Adults: Systematic Review Study.Immun Inflamm Dis. 2024 Nov;12(11):e70076. doi: 10.1002/iid3.70076. Immun Inflamm Dis. 2024. PMID: 39570098 Free PMC article.
References
-
- Centers for Disease Control and Prevention. COVID-19 vaccination for people who are pregnant or breastfeeding [Internet]. 2024 [cited 2024 Sep 30]. Available from: https://www.cdc.gov/covid/vaccines/pregnant-or-breastfeeding.html
-
- World Health Organization. Report of the SAGE Working Group on vaccine hesitancy [Internet]. 2014 Nov. Available from: https://www.who.int/docs/default-source/immunization/sage/2014/october/s...
-
- World Health Organization. Ten threats to global health in 2019 [Internet]. 2019 [cited 2024 Oct 10]. Available from: https://www.who.int/news-room/spotlight/ten-threats-to-global-health-in-...
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical