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. 2025 Aug 8;15(1):29069.
doi: 10.1038/s41598-025-14986-x.

Efficacy analysis of high-intensity laser therapy for post lumbar surgery syndrome

Affiliations

Efficacy analysis of high-intensity laser therapy for post lumbar surgery syndrome

Ruizhao Zhao et al. Sci Rep. .

Abstract

This retrospective cohort study investigated the efficacy of high-intensity laser therapy (HILT) in patients with the Post-Lumbar Surgery Syndrome (PLSS). The study analyzed patients diagnosed with PLSS who were admitted to our hospital between 2020 and 2023. In this study, patients were grouped by past treatment: Group A (oral medication) and Group B (high-intensity laser therapy plus oral medication).We conducted a comprehensive review of medical records to compare longitudinal outcomes, including visual analog scale (VAS) scores of low back pain, Oswestry Disability Index (ODI) assessments, and paraspinal muscle fat infiltration levels. Data were extracted at multiple time points: pre-treatment baseline, as well as post-treatment intervals of one week, one month, three months, six months, and twelve months. At 3-month and 6-month post-treatment, VAS scores of Group B were significantly lower than those of Group A (P < 0.001). At 12-month post-treatment, the ODI of Group B was significantly lower than that of Group A (P < 0.05). In patients of Group B, HILT may demonstrate a positive effect on the lumbar paraspinal muscles fat infiltration (PMFI) (P < 0.001). HILT demonstrates efficacy in alleviating clinical symptoms of PLSS and represents a viable adjuvant therapy for symptom management.

Keywords: Gabapentin; High-Intensity laser therapy; Paraspinal muscle fat infiltration; Post lumbar surgery syndrome.

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Conflict of interest statement

Declarations. Competing interests: The authors declare no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Quantitative analysis of PMFI (multifidus and erector spinae) at the L4/L5 lumbar level using Image J.
Fig. 2
Fig. 2
Comparison of VAS scores Between Two Groups.
Fig. 3
Fig. 3
Comparison of ODI Scores Between Two Groups. Data are shown as ns (not significant) = p value > 0.05, ∗ = p value < 0.05, ∗∗ = p value < 0.01, ∗∗∗ = p value < 0.001, and ∗∗∗∗ = p value < 0.0001. Group A; the Oral Medication Group; Group B; the high-intensity laser therapy plus oral medication Group.

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