Are physical activity, sleep, and joint pain associated with physical function and quality of life in individuals with multimorbidity? A cross-sectional analysis of the MOBILIZE trial

Travis Haber¹, Alessio Bricca^{2

3}, Michelle Hall⁴, Jan Christian Brønd⁵, Lau Thygesen⁶, Søren T Skou^{2

3}

Affiliations

¹ Centre for Health, Exercise and Sports Medicine, Department of Physiotherapy, The University of Melbourne, Melbourne, Australia. travis.haber@unimelb.edu.au.
² Department of Physiotherapy and Occupational Therapy, The Research and Implementation Unit PROgrez, Slagelse, Denmark.
³ Department of Sports Science and Clinical Biomechanics, Research Unit for Musculoskeletal Function and Physiotherapy, University of Southern Denmark, Odense, Denmark.
⁴ Sydney Musculoskeletal Health, The Kolling Institute, School of Health Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
⁵ Department of Sports Science and Clinical Biomechanics, Research Unit for Exercise Epidemiology, Center of Research in Childhood Health, University of Southern Denmark, Odense, Denmark.
⁶ National Institute of Public Health, University of Southern Denmark, Odense, Denmark.

PMID: 40782142
DOI: 10.1007/s11136-025-04044-4

Are physical activity, sleep, and joint pain associated with physical function and quality of life in individuals with multimorbidity? A cross-sectional analysis of the MOBILIZE trial

Travis Haber et al. Qual Life Res. 2025.

. 2025 Aug 9.

doi: 10.1007/s11136-025-04044-4. Online ahead of print.

Authors

Travis Haber¹, Alessio Bricca^{2

3}, Michelle Hall⁴, Jan Christian Brønd⁵, Lau Thygesen⁶, Søren T Skou^{2

3}

Affiliations

¹ Centre for Health, Exercise and Sports Medicine, Department of Physiotherapy, The University of Melbourne, Melbourne, Australia. travis.haber@unimelb.edu.au.
² Department of Physiotherapy and Occupational Therapy, The Research and Implementation Unit PROgrez, Slagelse, Denmark.
³ Department of Sports Science and Clinical Biomechanics, Research Unit for Musculoskeletal Function and Physiotherapy, University of Southern Denmark, Odense, Denmark.
⁴ Sydney Musculoskeletal Health, The Kolling Institute, School of Health Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
⁵ Department of Sports Science and Clinical Biomechanics, Research Unit for Exercise Epidemiology, Center of Research in Childhood Health, University of Southern Denmark, Odense, Denmark.
⁶ National Institute of Public Health, University of Southern Denmark, Odense, Denmark.

PMID: 40782142
DOI: 10.1007/s11136-025-04044-4

No abstract available

Keywords: Comorbidities; Exercise; Osteoarthritis; Physical function; Quality of life; Sleep.

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Conflict of interest statement

Declarations. Competing interests: STS is co-founder of Good Life with Osteoarthritis in Denmark (GLA: D®), a not-for profit initiative hosted at University of Southern Denmark aiming at implementing clinical guidelines for persons with osteoarthritis in clinical practice. The authors declare that there is no other conflict of interest.

References

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1. Skou, S. T., Mair, F. S., Fortin, M., Guthrie, B., Nunes, B. P., Miranda, J. J., Boyd, C. M., Pati, S., Mtenga, S., & Smith, S. M. (2022). Multimorbidity Nature Reviews Disease Primers, 8(1), 48. https://doi.org/10.1038/s41572-022-00376-4 - DOI - PubMed
1. Nguyen, H., Manolova, G., Daskalopoulou, C., Vitoratou, S., Prince, M., & Prina, A. M. (2019). Prevalence of Multimorbidity in community settings: A systematic review and meta-analysis of observational studies. Journal of Comorbidity, 9, 2235042X19870934. https://doi.org/10.1177/2235042X19870934 - DOI - PubMed - PMC
1. Chowdhury, S. R., Das, C., Sunna, D., Beyene, T. C., J., & Hossain, A. (2023). Global and regional prevalence of Multimorbidity in the adult population in community settings: A systematic review and meta-analysis. eClinicalMedicine, 5, 101860. https://doi.org/10.1016/j.eclinm.2023.101860 - DOI
1. Makovski, T. T., Schmitz, S., Zeegers, M. P., Stranges, S., & van den Akker, M. (2019). Multimorbidity and quality of life: Systematic literature review and meta-analysis. Ageing Research Reviews, 53, 100903. https://doi.org/10.1016/j.arr.2019.04.005 - DOI - PubMed

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Are physical activity, sleep, and joint pain associated with physical function and quality of life in individuals with multimorbidity? A cross-sectional analysis of the MOBILIZE trial

Affiliations

Are physical activity, sleep, and joint pain associated with physical function and quality of life in individuals with multimorbidity? A cross-sectional analysis of the MOBILIZE trial

Authors

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Conflict of interest statement

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