Which slot scanning device is best for low-dose radiographs in pediatric scoliosis? A pilot study
- PMID: 40782304
- DOI: 10.1007/s43390-025-01159-z
Which slot scanning device is best for low-dose radiographs in pediatric scoliosis? A pilot study
Abstract
Purpose: Studies have demonstrated a higher lifetime risk of cancer in AIS patients compared to age-matched controls. An asynchronous slot scan feature with ultra-small angle tomosynthesis reconstruction recently became available at our institution. Thus, we aimed to compare the performance of this new technology to the existing biplanar slot scanner for scoliosis imaging using standard dose settings.
Methods: All scoliosis patients under 18 years old from a single institution who underwent diagnostic imaging with both the asynchronous (True2Scale) and biplanar imaging system (EOS®) were included. Overall image quality was independently reviewed using a previously published method. Anthropomorphic phantom evaluations and dose measurements were conducted, with effective doses compared between systems. A computerized model based on phantom data estimated standardized patient effective doses.
Results: 40 imaging studies from 20 patients met the inclusion criteria. ICC for overall image quality was 0.88, with weighted-Cohen's Kappa analysis showing very high agreement (κ = 0.873). On average, patients imaged with the asynchronous system received 0.23 ± 0.15 (median: 0.10) mSv in each study, while patients imaged with the biplanar system received 0.12 ± 0.05 (median: 0.13) mSv. A bootstrap Welch's t-test showed a significant difference in mean radiation doses (p = 0.038, mean difference = 0.11 mSv, T2S higher than EOS). AP dose analysis showed no significant difference (p = 0.196), with the asynchronous system at 0.07 ± 0.03 (median: 0.07) mSv and biplanar at 0.06 ± 0.02 (median: 0.05) mSv.
Conclusions: Both technologies with standard dose parameters provided comparable image quality. While the asynchronous system delivers slightly higher radiation doses, both systems expose patients to less than annual background radiation (3 mSv) and standard 2-view scoliosis imaging doses. Larger studies are warranted to confirm these pilot findings.
Level of evidence: III-retrospective cohort study.
Keywords: Asynchronous slot scan; Biplanar slot scanner; Image quality; Radiation dose; Scoliosis.
© 2025. The Author(s), under exclusive licence to Scoliosis Research Society.
Conflict of interest statement
Declarations. Conflict of interest: Dr. Larson is a consultant for Highridge, Orthopediatrics, DePuy Synthes, Medtronic, and Pacira, with all funds directed to Mayo Clinic. Dr. Larson and Mayo Clinic receive royalties from Globus. Dr. Milbrandt is a consultant to Medtronic, with all funds directed to Mayo Clinic. Mayo Clinic has patent 10667845B2, with Drs. Larson and Milbrandt as inventors, and has received research funding from Orthopediatrics and Medtronic. No conflicts of interest by any author are directly related to this study.
Similar articles
-
Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis.Cochrane Database Syst Rev. 2020 Oct 19;10(10):CD012859. doi: 10.1002/14651858.CD012859.pub2. Cochrane Database Syst Rev. 2020. PMID: 33075160 Free PMC article.
-
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.Cochrane Database Syst Rev. 2017 Dec 22;12(12):CD011535. doi: 10.1002/14651858.CD011535.pub2. Cochrane Database Syst Rev. 2017. Update in: Cochrane Database Syst Rev. 2020 Jan 9;1:CD011535. doi: 10.1002/14651858.CD011535.pub3. PMID: 29271481 Free PMC article. Updated.
-
EOS 2D/3D X-ray imaging system: a systematic review and economic evaluation.Health Technol Assess. 2012;16(14):1-188. doi: 10.3310/hta16140. Health Technol Assess. 2012. PMID: 22449757 Free PMC article.
-
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.Cochrane Database Syst Rev. 2020 Jan 9;1(1):CD011535. doi: 10.1002/14651858.CD011535.pub3. Cochrane Database Syst Rev. 2020. Update in: Cochrane Database Syst Rev. 2021 Apr 19;4:CD011535. doi: 10.1002/14651858.CD011535.pub4. PMID: 31917873 Free PMC article. Updated.
-
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.Cochrane Database Syst Rev. 2021 Apr 19;4(4):CD011535. doi: 10.1002/14651858.CD011535.pub4. Cochrane Database Syst Rev. 2021. Update in: Cochrane Database Syst Rev. 2022 May 23;5:CD011535. doi: 10.1002/14651858.CD011535.pub5. PMID: 33871055 Free PMC article. Updated.
Cited by
-
Racial, ethnic and socioeconomic disparities in healthcare for adult spinal deformity patients.Spine Deform. 2025 Sep;13(5):1539-1546. doi: 10.1007/s43390-025-01118-8. Epub 2025 May 28. Spine Deform. 2025. PMID: 40437324
References
-
- Komang-Agung IS, Dwi-Purnomo SB, Susilowati A (2017) Prevalence rate of adolescent idiopathic scoliosis: results of school-based screening in Surabaya. Indonesia Malays Orthop J 11(3):17–22 - PubMed
-
- Penha PJ, Ramos NLJP, de Carvalho BKG, Andrade RM, Schmitt ACB, João SMA (2018) Prevalence of adolescent idiopathic scoliosis in the state of São Paulo, Brazil. Spine (Phila Pa 1976) 43(24):1710–1718 - PubMed
-
- Simony A, Hansen EJ, Christensen SB, Carreon LY, Andersen MO (2016) Incidence of cancer in adolescent idiopathic scoliosis patients treated 25 years previously. Eur Spine J 25(10):3366–3370 - PubMed
LinkOut - more resources
Research Materials
Miscellaneous