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. 2025 Aug 9;100(5):501177.
doi: 10.1016/j.abd.2025.501177. Online ahead of print.

Posterior reversible encephalopathy syndrome in a patient treated with Ustekinumab

Marilda Aparecida Milanez Morgado de Abreu  1 , Naíra M de A Guaresemin  2 , Murilo de Oliveira Lima Carapeba  3
Affiliations

Posterior reversible encephalopathy syndrome in a patient treated with Ustekinumab

Marilda Aparecida Milanez Morgado de Abreu et al. An Bras Dermatol. .
No abstract available

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Conflict of interest statement

Conflicts of interest None declared.

Figures

Figure 1
Figure 1
Magnetic resonance imaging of the brain. (a) FLAIR (fluid-attenuated inversion recovery) showing small foci of hyperintense signal in the periventricular and subcortical white matter of the bilateral frontal and parietal lobes. (b) DWI (diffusion-weighted imaging) showing hyperintense signal from the punctate foci seen on FLAIR (fluid-attenuated inversion recovery), suggesting cytotoxic edema. (c) ADC (apparent diffusion coefficient) MAP confirms the diffusion findings, showing restricted diffusion.
See this image and copyright information in PMC

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References

    1. Silva D.L.F.D., Secamilli E.N., Beleli M.V., Massuda J.Y., Franca A.F.E.C., Magalhães R.F. Immunobiologicals in dermatology. An Bras Dermatol. 2022;97:275–283. - PMC - PubMed
    1. Gratton D., Szapary P., Goyal K., Fakharzadeh S., Germain V., Saltiel P. Reversible posterior leukoencephalopathy syndrome in a patient treated with ustekinumab: case report and review of the literature. Arch Dermatol. 2011;147:1197–1202. - PubMed
    1. Dickson L., Menter A. Reversible posterior leukoencephalopathy syndrome (RPLS) in a psoriasis patient treated with ustekinumab. J Drugs Dermatol. 2017;16:177–179. - PubMed
    1. Mishra A., Seril D.N. Posterior reversible encephalopathy syndrome following ustekinumab induction for Crohn’s disease. Case Rep Gastroenterol. 2018;12:521–527. - PMC - PubMed
    1. Jordan A., Kinnucan J. Ustekinumab-associated posterior reversible encephalopathy syndrome in a patient with Crohn’s disease. ACG Case Rep J. 2022;9 - PMC - PubMed

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