Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Aug 1;15(8):7656-7662.
doi: 10.21037/qims-2024-2546. Epub 2025 Jul 11.

Accelerated knee osteoarthritis: a case description and literature analysis

Affiliations

Accelerated knee osteoarthritis: a case description and literature analysis

Weipeng Xie et al. Quant Imaging Med Surg. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://qims.amegroups.com/article/view/10.21037/qims-2024-2546/coif). All authors report that this study was supported by the General Program of Talent Cultivation of Xi’an Municipal Commission of Health Planning (2021ms10) and Osteoarthritis Risk Factor Screening and Clinical Translation Innovative Team (No. 2024RS-CXTD-86). The authors have no other conflicts of interest to declare.

Figures

Figure 1
Figure 1
Radiographic and clinical progression of bilateral knee osteoarthritis with total knee arthroplasty: from mild to severe degeneration and postoperative outcomes. (A-C) Mild degenerative changes in both knee joints, the right knee (K-L grade III) and left knee (K-L grade I or II), as shown on the radiographs taken at the local hospital 1.5 years ago; (D-F) severe degenerative changes in both knee joints as shown on the radiographs taken after admission to the hospital (K-L grade IV), with the right knee being the heaviest; (G,H) intraoperative photographs during knee flexion and extension; (I) two tubes of joint fluid withdrawn intraoperatively; (J-L) a 29-month postoperative radiograph of the TKA. K-L, Kellgren-Lawrence; TKA, total knee arthroplasty.
Figure 2
Figure 2
Treatment process. AKOA, accelerated knee osteoarthritis; KSS, Knee Society Score; NGS, next-generation sequencing; TKA, total knee arthroplasty.

Similar articles

References

    1. Liew JW, King LK, Mahmoudian A, Wang Q, Atkinson HF, Flynn DB, Appleton CT, Englund M, Haugen IK, Lohmander LS, Runhaar J, Neogi T, Hawker G, OARSI Early Osteoarthritis Classification Criteria Task Force . A scoping review of how early-stage knee osteoarthritis has been defined. Osteoarthritis Cartilage 2023;31:1234-41. 10.1016/j.joca.2023.04.015 - DOI - PMC - PubMed
    1. Lv Z, Yang YX, Li J, Fei Y, Guo H, Sun Z, Lu J, Xu X, Jiang Q, Ikegawa S, Shi D. Molecular Classification of Knee Osteoarthritis. Front Cell Dev Biol 2021;9:725568. 10.3389/fcell.2021.725568 - DOI - PMC - PubMed
    1. Driban JB, Eaton CB, Lo GH, Ward RJ, Lu B, McAlindon TE. Association of knee injuries with accelerated knee osteoarthritis progression: data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken) 2014;66:1673-9. 10.1002/acr.22359 - DOI - PMC - PubMed
    1. Driban JB, Price LL, Eaton CB, Lu B, Lo GH, Lapane KL, McAlindon TE. Individuals with incident accelerated knee osteoarthritis have greater pain than those with common knee osteoarthritis progression: data from the Osteoarthritis Initiative. Clin Rheumatol 2016;35:1565-71. 10.1007/s10067-015-3128-2 - DOI - PMC - PubMed
    1. Driban JB, Bannuru RR, Eaton CB, Spector TD, Hart DJ, McAlindon TE, Lu B, Lo GH, Arden NK. The incidence and characteristics of accelerated knee osteoarthritis among women: the Chingford cohort. BMC Musculoskelet Disord 2020;21:60. 10.1186/s12891-020-3073-3 - DOI - PMC - PubMed

LinkOut - more resources