Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jul;67(7):659-665.
doi: 10.4103/indianjpsychiatry_86_25. Epub 2025 Jul 15.

Two-year outcome of a treatment program for alcohol use disorder in regional and rural India

Affiliations

Two-year outcome of a treatment program for alcohol use disorder in regional and rural India

Chellamuthu Ramasubramanian et al. Indian J Psychiatry. 2025 Jul.

Abstract

Background: Alcohol use disorder (AUD) is a major health issue in developing countries, posing a significant economic burden with limited access to comprehensive treatment and follow-up services. AUD treatment services are limited in India, especially in regional and rural areas.

Methods: This retrospective study assessed outcomes in patients with AUD from a rural and regional part of India admitted to a voluntary treatment program with a 2-year follow-up after initial detoxification. The primary outcome measures were the extent and duration of abstinence achieved at the end of 2 years. The secondary outcome measures were quality of life, psychological wellbeing, and family burden.

Results: One hundred sixty-nine out of 180 patients (93.9%) completed the 2-year program. Sustained abstinence was achieved by 81.1% of patients and sustained low-risk drinking by 14.8% in an uncontrolled environment. There was a significant improvement in the quality of life and psychological wellbeing and a reduction in the total family burden. Patients sustaining total abstinence experienced a higher family burden at intake than those with low-risk drinking.

Conclusion: The majority of patients with AUD achieved total abstinence in communities with limited specialist health services with appropriate treatment and follow-up services. Factors influencing such positive outcomes could be the voluntary nature of the program, setting up total abstinence as the treatment goal, collaborative support of the family, access to low-cost treatment and extended follow-up, and use of disulfiram. A future prospective study using a control group addressing this study's limitations is required to confirm the observed outcomes.

Keywords: Alcohol use disorder; India; social capital; treatment outcome.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Similar articles

References

    1. Rehm J, Shield KD. Global burden of disease and the impact of mental and addictive disorders. Curr Psychiatry Rep. 2019;21:10. - PubMed
    1. World Health Organisation Global Status Report on Alcohol and Health. 2014. Available from: https://www.who.int/publications/i/item/global-status-report-on-alcohol-... . [Last accessed on 2024 Dec 20]
    1. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders. 2013
    1. Saxena S. Disease Control Priorities Related to Mental, Neurological, Developmental and Substance Abuse Disorders. Vol. 10. Geneva: World Health Organisation; 2006. Conclusion; pp. 101–3.
    1. Sujiv A, Chinnakali P, Balajee K, Lakshminarayanan S, Kumar SG, Roy G. Alcohol use and alcohol use disorder among male outpatients in a primary care setting in rural Puducherry. Ind Psychiatry J. 2015;24:135–9. - PMC - PubMed

LinkOut - more resources