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. 2025 Jul 19;14(3):246-253.
doi: 10.4103/gmit.GMIT-D-24-00033. eCollection 2025 Jul-Sep.

Comparison of Prognosis between Abdominal and Laparoscopic Radical Hysterectomies in Early-stage Cervical Cancer: A Retrospective Cohort Study

I-Chun Huang  1 , Pei-Chen Li  1 , Dah-Ching Ding  1   2
Affiliations

Comparison of Prognosis between Abdominal and Laparoscopic Radical Hysterectomies in Early-stage Cervical Cancer: A Retrospective Cohort Study

I-Chun Huang et al. Gynecol Minim Invasive Ther. .

Abstract

Objectives: There is still ongoing debate regarding the surgical approach for early-stage cervical cancer. We aimed to compare the outcomes of abdominal radical hysterectomy (ARH) and laparoscopic radical hysterectomy (LRH) in patients with early-stage cervical cancer and compare our results with those of previous studies.

Materials and methods: This study included patients with early-stage cervical cancer (International Federation of Gynecology and Obstetrics ≤ stage IIA) who received treatment from January 2002 to December 2022. Clinical, surgical, pathological, recurrence, and survival data were collected and analyzed using suitable statistical methods.

Results: Of the 71 patients, 54 underwent ARH and 17 underwent LRH. The median follow-up durations were 117.0 months for the ARH group and 64.4 months for the LRH group. The average age of patients was 53.7 years, with a mean body mass index of 24.2 kg/m2. Most patients had stage IB1 disease, and squamous cell carcinoma was the most common histological type. ARH was performed in 76.1% of patients, while 23.9% underwent LRH. LRH patients had significantly less blood loss (180 ml vs. 871.7 ml) and shorter hospital stays (6 days vs. 14 days). No significant differences in disease recurrence, cervical cancer-related mortality, or overall survival were observed between the two groups.

Conclusion: Early-stage cervical cancer patients who received LRH had survival and recurrence outcomes comparable to those who underwent ARH.

Keywords: Cervical cancer; minimally invasive surgery; open surgery; recurrence; survival.

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Conflict of interest statement

Dr. Dah-Ching Ding, an editorial board member at Gynecology and Minimally Invasive Therapy, had no role in the peer review process of or decision to publish this article. All authors declared no conflicts of interest in writing this paper.

Figures

Figure 1
Figure 1
Kaplan–Meier plot of disease-free survival of cervical cancer patients who received abdominal or laparoscopic radical hysterectomy (LRH). The hazard ratio and 95% confidence interval were estimated using Cox proportional hazards models. Disease recurrence occurred in 8 of 54 in abdominal radical hysterectomy and 4 of 17 in LRH
Figure 2
Figure 2
Kaplan–Meier plot of overall survival of cervical cancer patients who received abdominal or laparoscopic radical hysterectomy (LRH). The hazard ratio and 95% confidence interval were estimated using Cox proportional hazards models. Death occurred in 8 of 54 in abdominal radical hysterectomy and 0 of 17 in LRH
Figure 3
Figure 3
Kaplan–Meier plot of disease-specific survival of cervical cancer patients who received abdominal or laparoscopic radical hysterectomy (LRH). The hazard ratio and 95% confidence interval were estimated using Cox proportional hazards models. Death from cervical cancer occurred in 4 of 54 in abdominal radical hysterectomy and 0 of 17 in LRH
Figure 4
Figure 4
Kaplan–Meier plot of locoregional recurrence of cervical cancer patients who received abdominal or laparoscopic radical hysterectomy (LRH). The hazard ratio and 95% confidence interval were estimated using Cox proportional hazards models. Locoregional recurrence occurred in 7 of 54 in abdominal radical hysterectomy and 4 of 17 in LRH
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