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Case Reports
. 2025 Jun 25:63:34-37.
doi: 10.1016/j.jdcr.2025.06.022. eCollection 2025 Sep.

Recalcitrant epidermolysis bullosa acquisita treated with upadacitinib as a bridge to rituximab

Taha Rasul  1 , Anthony Concilla  1 , Michelle Militello  1 , Paola Torres  1 , Angelia Stepien  1
Affiliations
Case Reports

Recalcitrant epidermolysis bullosa acquisita treated with upadacitinib as a bridge to rituximab

Taha Rasul et al. JAAD Case Rep. .
No abstract available

Keywords: JAK inhibitors; autoimmune blistering disease; bridging therapy; epidermolysis bullosa acquisita; mechanobullous EBA; refractory dermatologic disease; rituximab; upadacitinib.

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Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
Initial presentation of extensive tense bullae, erosions, and crusting predominantly affecting the breasts (A) and extremities (B), consistent with mechanobullous EBA. EBA, Epidermolysis bullosa acquisita.
Fig 2
Fig 2
A and B, Marked improvement of skin lesions following initiation of upadacitinib and subsequent rituximab therapy, with resolution of erosions. Postinflammatory hyperpigmentation and milia at sites of scarring can be seen.
See this image and copyright information in PMC

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References

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