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. 2025 Aug 7;10(5):e1315.
doi: 10.1097/PR9.0000000000001315. eCollection 2025 Oct.

Validation of the menstrual sensitivity index in adolescents

Affiliations

Validation of the menstrual sensitivity index in adolescents

Laura C Seidman et al. Pain Rep. .

Abstract

Introduction: The Menstrual Sensitivity Index (MSI), assessing the attunement to and fear of menstrual symptoms, was recently developed and validated in an adult sample.

Objectives: The objective of this study was to validate the MSI in adolescents.

Methods: One hundred forty-one girls aged 13 to 19 participated in a larger parent study on primary dysmenorrhea, and their data were used in the present study. Girls participated at 2 timepoints: baseline (N = 141) and a 1-year follow-up (N = 115). At each timepoint, participants completed the MSI and a variety of self-report measures.

Results: A confirmatory factor analysis supports the previously identified factors of the MSI (somatic anxiety, fear/danger, and medication) in adolescent girls. The MSI demonstrates good item-total correlations, internal consistency, and test-retest reliability. The MSI converged most strongly with pain catastrophizing and diverged most strongly from body pain.

Conclusion: The MSI is a valid and reliable measure of attunement to and fear of menstrual symptoms in adolescents. Unlike research in adult women demonstrating convergence between the MSI and menstrual pain and menstrual symptom severity, the divergence between the MSI and these variables in the current study suggests that, for adolescents, menstrual sensitivity is more strongly related to fear of pain than menstrual pain itself. These findings provide considerations for future research and clinical practice addressing menstrual pain and symptoms in adolescents.

Keywords: Adolescents; Dysmenorrhea; Menstrual pain; Menstrual sensitivity; Scale development.

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Conflict of interest statement

L.A.P. has received consulting fees from Bayer Healthcare, Mahana Therapeutics, and Oregon Health & Science University and speaking fees from Brightside Health, Pacific Rehabilitation Centers, and The Concord Center. This study was supported by a grant from the National Institute of Child Health and Human Development (R01 HD093680; PI: L.A.P.).Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.

Figures

Figure 1.
Figure 1.
Participant recruitment and enrollment flow diagram. ADHD, attention deficit hyperactivity disorder; PD, primary dysmenorrhea.

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