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Randomized Controlled Trial
. 2025 Jun 25;26(4):1112-1119.
doi: 10.5811/westjem.34871.

Randomized Trial of Self-Selected Music Intervention on Pain and Anxiety in Emergency Department Patients with Musculoskeletal Back Pain

Affiliations
Randomized Controlled Trial

Randomized Trial of Self-Selected Music Intervention on Pain and Anxiety in Emergency Department Patients with Musculoskeletal Back Pain

Charlotte E Goldfine et al. West J Emerg Med. .

Abstract

Introduction: Acute musculoskeletal back pain is a frequent cause of emergency department (ED) visits, often with suboptimal relief from standard treatments. Recent evidence suggests listening to music may modulate pain and anxiety. In this pilot randomized controlled trial, we evaluated the impact of a brief session of patient-selected music vs noise cancellation on pain severity and anxiety in patients presenting to the ED with back pain.

Methods: Patients with acute back pain completed a baseline survey to assess demographics, medication information, and psychosocial factors. The ED patients were randomized to listen to self-selected music or to noise cancellation (control). Patients rated their pain and anxiety (0-10) before and immediately after the intervention. We used analyses of covariance to examine whether post-intervention pain and anxiety differed between the groups, while controlling for baseline trait pain catastrophizing. A mediation analysis was conducted to explore the role of post-intervention anxiety as a mediator of the group difference in post-intervention pain.

Results: Forty patients were enrolled with an average age of 47.2 years (range 21 - 81). and 27 patients (68%) were female. At baseline, patients in the music group reported higher pain catastrophizing compared to patients in the noise cancellation group. There were no other group differences in baseline characteristics. Post-intervention, patients in the music group reported significantly lower anxiety (3.0 ± 0.7 vs 5.5 ± 0.7, P = 0.016) and pain severity (6.1 ± 0.4 vs.7.5 ± 0.4, P = 0.037) compared to the noise cancellation group. A mediation analysis showed that post-intervention anxiety partially mediated the association between intervention group (music vs noise cancellation) and post-intervention pain.

Conclusion: A brief session of self-selected music resulted in lower pain and anxiety scores than noise cancellation among patients with musculoskeletal back pain in the ED. Patients who listened to music reported lower post-intervention anxiety, which partially contributed to lower post-intervention pain severity.

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Conflict of interest statement

Conflicts of Interest: By the WestJEM article submission agreement, all authors are required to disclose all affiliations, funding sources and financial or management relationships that could be perceived as potential sources of bias. This research was supported by an unrestricted donation from Mr. David Solomon. PRC reports funding by NIH DP2DA056107 and R25DA058490, Bill and Melinda Gates Foundation. PRC also owns equity in Biobot Analytics and is a medical consultant for Syntis Bio and Equalizer Future Health. CEG funded by Bill and Melinda Gates Foundation. KLS reports funding by NIH R35GM128691. Outside of this work, SGW reports funding by NIH R01DA044167, R01HS026753, and R01DA058315, is a medical consultant to Vertex Pharmaceuticals, Inc. and Cessation Therapeutics, Inc. No other author has professional or financial relationships with any companies that are relevant to this study. There are no other conflicts of interest or sources of funding to declare.

Figures

Figure 1
Figure 1
Study flow diagram for effect of music on musculoskeletal low back pain in the emergency department.
Figure 2
Figure 2
Differences in post-intervention (A) pain and (B) anxiety based on intervention group, controlling for baseline PCS. PCS, pain catastrophizing scores.
Figure 3
Figure 3
Greater post-intervention anxiety was correlated with greater post-intervention pain (r=0.54, P <0.001).
Figure 4
Figure 4
The mediating effect of post-intervention anxiety in the relationship between the music intervention and post-intervention pain, controlling for baseline Pain Catastrophizing Scale score * P <.05.

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