Comparative analysis of newest-generation variable-diameter cryoballoon with pulsed-field ablation for the treatment of atrial fibrillation: the CRYO-PULSE Study
- PMID: 40795141
- PMCID: PMC12395424
- DOI: 10.1093/europace/euaf166
Comparative analysis of newest-generation variable-diameter cryoballoon with pulsed-field ablation for the treatment of atrial fibrillation: the CRYO-PULSE Study
Keywords: Atrial fibrillation; Catheter ablation; Cryoballoon ablation; Pulmonary vein isolation; Pulsed-field ablation.
Conflict of interest statement
Conflict of interest: B.S. reports receiving a travel grant from Boston Scientific outside the submitted work. P.B. has received research funding from the ‘University of Basel’, the ‘Stiftung für Herzschrittmacher und Elektrophysiologie’, the ‘Freiwillige Akademische Gesellschaft Basel’, the ‘Swiss Heart Foundation’, and Johnson & Johnson and reports personal fees from BMS, Boston Scientific, and Abbott, all outside the submitted work. S.K. has received funding from the ‘Stiftung für Herzschrittmacher und Elektrophysiologie’. F.M. is supported by Deutsche Forschungsgemeinschaft (SFB TRR219, Project-ID 322900939) and Deutsche Herzstiftung. Until May 2024, F.M. has received speaker honoraria/consulting fees from Ablative Solutions, AstraZeneca, Inari, Medtronic, Merck, Novartis, Philips, and Recor Medical, all outside the submitted work. P.K. reports research grants from the Swiss National Science Foundation, Swiss Heart Foundation, the Machaon Foundation, and the Foundation for Cardiovascular Research Basel and speaking fees from BMS/Pfizer and JnJ Medtech, all outside the submitted work. C.S. is a member of Medtronic Advisory Board Europe and Boston Scientific Advisory Board Europe and received educational grants from Biosense Webster and Biotronik and a research grant from the European Union’s FP7 programme and Biosense Webster and lecture and consulting fees from Abbott, Medtronic, Biosense Webster, Boston Scientific, MicroPort, and Biotronik, all outside the submitted work. M.K. reports grants from the Swiss National Science Foundation (grant numbers 33CS30_148474, 33CS30_177520, 32473B_176178, and 32003B_197524), the Swiss Heart Foundation, the Foundation for Cardiovascular Research Basel, and the University of Basel, grants from Bayer, grants from BMS, grants from Boston Scientific, grants from Daiichi Sankyo, grants from Pfizer, personal fees from Abbott, personal fees from Boston Scientific, personal fees from Daiichi Sankyo, and royalties from Springer Nature, all outside the submitted work. J.P.W. received funding from the German Foundation of Heart Research (F/29/19), speaker fees from Abbott and Doctrina Med, and travel grants from Boston Scientific, all outside the submitted work. C.-H.H. received travel grants and research grants from Boston Scientific, Liftech, Biosense Webster, and Haemonetics and speaker honoraria from Boston Scientific, Biosense Webster, Pfizer, Haemonetics, BMS, C.T.I. GmbH, and Doctrina Med. C.E. received travel grants and research grants from Abbott, Boston Scientific, Liftech, Biosense Webster, and Cardiofocus and speaker honoraria from Abbott, Boston Scientific, Biosense Webster, Cardiofocus, C.T.I. GmbH, and Doctrina Med, all outside the submitted work. K.-H.K. reports grants and personal fees from Abbott Vascular, Medtronic, and Biosense Webster, all outside the submitted work. R.T. is a consultant for Abbott, Boston Scientific, Biotronik, and Biosense Webster and received speaker honoraria from Biosense Webster, Medtronic, Boston Scientific, and Abbot Medical, all outside the submitted work. All other authors have nothing to declare.
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References
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- Reichlin T, Kueffer T, Badertscher P, Jüni P, Knecht S, Thalmann G et al. Pulsed field or cryoballoon ablation for paroxysmal atrial fibrillation. N Engl J Med 2025;392:1497–507. - PubMed
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- Reddy VY, Gerstenfeld EP, Natale A, Whang W, Cuoco FA, Patel C et al. Pulsed field or conventional thermal ablation for paroxysmal atrial fibrillation. N Engl J Med 2023;389:1660–71. - PubMed
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