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Review
. 2025 Aug 7;31(29):110133.
doi: 10.3748/wjg.v31.i29.110133.

Mechanism of action of heat-clearing and detoxifying herbs in the treatment of erosive gastritis

Fang Zhou  1 , Yi-Tong Sun  1 , Hong-Xin Zheng  2 , Jing-Dong Xiao  3
Affiliations
Review

Mechanism of action of heat-clearing and detoxifying herbs in the treatment of erosive gastritis

Fang Zhou et al. World J Gastroenterol. .

Abstract

This article focuses on the clinical efficacy and mechanism of action of heat-clearing and detoxifying traditional Chinese medicines (TCMs) in the treatment of erosive gastritis, providing a reference for the treatment of this disease. In the clinical treatment of erosive gastritis, TCM combinations such as Qing Gastric San, Semixia Diarrheal Heart Soup, and single-flavored heat-clearing and detoxifying drugs such as dandelion and Huanglian have specific efficacies and effectively improve the patient's symptoms, including killing or inhibiting Helicobacter pylori, reducing inflammatory reactions, protecting the gastric mucosa, inhibiting gastric acid secretion, regulating gastrointestinal hormones, and regulating immune function, playing therapeutic roles through multi-level and multi-target mechanisms. Thus, heat-clearing and detoxifying TCMs have broad application prospects in clinical practice for erosive gastritis.

Keywords: Chronic gastritis with erosion; Clinical efficacy; Heat-clearing and detoxifying medicines; Mechanisms of action; Traditional Chinese medicine etiology and pathogenesis.

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Conflict of interest statement

Conflict-of-interest statement: Authors declare that they have no competing interests.

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