Navigating treatment sequencing in ALK-positive non-small cell lung cancer: lorlatinib as a key to prolonged survival?
- PMID: 40799441
- PMCID: PMC12337053
- DOI: 10.21037/tlcr-2025-373
Navigating treatment sequencing in ALK-positive non-small cell lung cancer: lorlatinib as a key to prolonged survival?
Keywords: Tyrosine kinase inhibitors (TKIs); anaplastic lymphoma kinase-positive non-small cell lung cancer (ALK-positive NSCLC); sequential therapies; toxicity.
Conflict of interest statement
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://tlcr.amegroups.com/article/view/10.21037/tlcr-2025-373/coif). The authors have no conflicts of interest to declare.
Comment on
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Final Overall Survival and Long-Term Safety of Lorlatinib in Patients With ALK-Positive NSCLC From the Pivotal Phase 2 Study: A Brief Report.J Thorac Oncol. 2025 Apr;20(4):513-520. doi: 10.1016/j.jtho.2024.11.021. Epub 2024 Nov 22. J Thorac Oncol. 2025. PMID: 39581380 Clinical Trial.
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