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Review
. 2025 Jul 29:13:1639423.
doi: 10.3389/fped.2025.1639423. eCollection 2025.

Risk factors for the development of necrotizing enterocolitis in neonatal hemolytic disease: a mini review

Haiyue Yu  1 , Wanxu Guo  1 , Yuan Wang  1 , Yunfeng Zhang  1
Affiliations
Review

Risk factors for the development of necrotizing enterocolitis in neonatal hemolytic disease: a mini review

Haiyue Yu et al. Front Pediatr. .

Abstract

Hemolytic disease of the newborn (HDN) is a common disease of neonates, and necrotizing enterocolitis (NEC) is a serious gastrointestinal disorder and both occur in the neonatal period that can significantly increase the risk of death in children. Cases of NEC associated with HDN are increasing. The purpose of this paper is to collect and present relevant research data to understand the risk factors associated with necrotizing enterocolitis in neonatal hemolytic disease, and to provide reasonable guidance and reference for clinical work.

Keywords: enterocolitis; exchange transfusion hemolytic; hemolytic; immunoglobulins; intravenous; necrotizing; newborn; risk factor.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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