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Review
. 2025 Jul-Aug;20(4):341-349.
doi: 10.1177/15569845251363231. Epub 2025 Aug 13.

State-of-the-Art Review: Operating Room Extubation

Affiliations
Review

State-of-the-Art Review: Operating Room Extubation

Rakesh C Arora et al. Innovations (Phila). 2025 Jul-Aug.

Abstract

Enhancing recovery protocols seek to optimize multiple aspects of care throughout the patient's perioperative cardiac surgery journey. Fast-track recovery protocols, specifically those involving earlier extubation, have been among the early methods to enhance a patient's recovery. However, how early these protocols should be implemented after surgery remains a source of ongoing controversy. Strong opinions exist on whether it is appropriate to extubate patients after cardiac surgery in the operating room (OR). Although OR extubation may offer benefits such as reduced intensive care unit length of stay and resource utilization, there are concerns regarding safety, patient selection, and inconsistent outcomes, which have raised significant controversy. This review aims to discuss the reasons why a team may consider exploring extubation in the OR and provide a practical approach for the interdisciplinary team seeking to implement this practice in appropriately selected patients.

Keywords: cardiac surgery; operating room extubation; ultra-fast track.

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Conflict of interest statement

Declaration of Conflicting InterestsThe authors declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: R.C.A. has received honoraria from Edwards Lifesciences, Medtronic, Serb Pharmaceuticals, HLS Therapeutics, and Bioporto. R.C.A. has also served on the Advisory Board for Alexion and Renibus Therapeutics Inc.

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