Bone and Cardiometabolic Connection: Crosstalk between Osteoporosis and Atherosclerosis

Karisma Sarangi^{1

2

3}, Sydney Sampson^{1

2}, Narasimham L Parinandi⁴, Mahdi Garelnabi^{5

6}

Affiliations

¹ Department of Biomedical and Nutritional Sciences, University of Massachusetts Lowell, Lowell, MA, USA.
² UMass Lowell Center for Population Health, University of Massachusetts Lowell, Lowell, MA, USA.
³ The Department of Biological Sciences, University of Massachusetts Lowell, Lowell, MA, USA.
⁴ Division of Pulmonary, Critical Care, and Sleep, Department of Medicine, and Dorothy Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Columbus, OH, USA.
⁵ Department of Biomedical and Nutritional Sciences, University of Massachusetts Lowell, Lowell, MA, USA. Mahdi_Garelnabi@uml.edu.
⁶ UMass Lowell Center for Population Health, University of Massachusetts Lowell, Lowell, MA, USA. Mahdi_Garelnabi@uml.edu.

Review

Karisma Sarangi et al. Cell Biochem Biophys. 2025 Dec.

. 2025 Dec;83(4):4287-4312.

doi: 10.1007/s12013-025-01851-x. Epub 2025 Aug 13.

Karisma Sarangi^{1

2

3}, Sydney Sampson^{1

2}, Narasimham L Parinandi⁴, Mahdi Garelnabi^{5

6}

¹ Department of Biomedical and Nutritional Sciences, University of Massachusetts Lowell, Lowell, MA, USA.
² UMass Lowell Center for Population Health, University of Massachusetts Lowell, Lowell, MA, USA.
³ The Department of Biological Sciences, University of Massachusetts Lowell, Lowell, MA, USA.
⁴ Division of Pulmonary, Critical Care, and Sleep, Department of Medicine, and Dorothy Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Columbus, OH, USA.
⁵ Department of Biomedical and Nutritional Sciences, University of Massachusetts Lowell, Lowell, MA, USA. Mahdi_Garelnabi@uml.edu.
⁶ UMass Lowell Center for Population Health, University of Massachusetts Lowell, Lowell, MA, USA. Mahdi_Garelnabi@uml.edu.

No abstract available

Keywords: Atherosclerosis; Bone; Cardiovascular disease; Inflammation; Osteoporosis; Vascular calcification.

Conflict of interest statement

Competing interests: The authors declare no competing interests.

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