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. 2025 Aug 8;78(3):e20240111.
doi: 10.1590/0034-7167-2024-0111. eCollection 2025.

Analysis of the SOFA score, quick-SOFA, and SIRS criteria in burn patients with infection

[Article in English, Portuguese]
Affiliations

Analysis of the SOFA score, quick-SOFA, and SIRS criteria in burn patients with infection

[Article in English, Portuguese]
Francielli Mary Pereira Gimenez et al. Rev Bras Enferm. .

Abstract

Objectives: to evaluate the SOFA score, qSOFA, SIRS criteria, and risk factors for hospital mortality in burn victims with suspected infection admitted to an intensive care unit.

Methods: a retrospective longitudinal study conducted at a public hospital between January 2017 and January 2020. We analyzed sepsis diagnostic scores at two time points: hospital admission and date of infection.

Results: of the 279 patients analyzed, 251 developed an infection. Among these, 145 had a positive SIRS score at the time of the burn, and 112 remained positive at the first documented infection. The SOFA score increased in 187 patients following the burn injury, and 34 remained positive at the time of infection.

Conclusions: the scores on the dates of burn injury and infection did not show variations in SIRS or SOFA compatible with sepsis diagnosis. Age, total body surface area burned, and SOFA score were independent risk factors for mortality.

Objetivos:: evaluar la puntuación SOFA, qSOFA, los criterios SIRS y los factores de riesgo de mortalidad hospitalaria en víctimas de quemaduras con sospecha de infección ingresadas en unidades de cuidados intensivos.

Métodos:: estudio longitudinal retrospectivo realizado en un hospital público entre enero de 2017 y enero de 2020. Se analizaron los puntajes para el diagnóstico de sepsis en dos momentos: admisión hospitalaria y fecha de la infección.

Resultados:: de 279 pacientes, 251 desarrollaron infección. Entre ellos, 145 presentaron SIRS positivo en la quemadura, manteniéndose 112 positivos en la infección. La variación del SOFA fue positiva en 187 pacientes en la quemadura, y 34 continuaron positivos en la infección.

Conclusiones:: los puntajes en las fechas de la quemadura e infección no mostraron variación de SIRS y SOFA compatible con el diagnóstico de sepsis. La edad, la superficie corporal quemada y el SOFA fueron factores de riesgo independientes para la mortalidad.

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References

    1. Kelly EJ, Oliver MA, Carney BC, Shupp JW. Infection and Burn Injury. Europ Burn J. 2022;3(1):165–179. doi: 10.3390/ebj3010014. - DOI - PMC - PubMed
    1. Burgess M, Valdera F, Varon D, Kankuri E, Nuutila K. The Immune and Regenerative Response to Burn Injury. Cells. 2022;11(19):3073. doi: 10.3390/cells11193073. - DOI - PMC - PubMed
    1. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) JAMA. 2016;315(8):801–810. doi: 10.1001/jama.2016.0287. - DOI - PMC - PubMed
    1. Chakraborty RK, Burns B. In: StatPearls. Treasure Island (FL): StatPearls Publishing;; 2024. [cited 2024 Jun 19]. Systemic Inflammatory Response Syndrome. [Internet] Available from: https://www.ncbi.nlm.nih.gov/books/NBK547669/
    1. Anand V, Zhang Z, Kadri SS, Klompas M, Rhee C, CDC Prevention epicenters program epidemiology of quick sequential organ failure assessment criteria in undifferentiated patients and association with suspected infection and sepsis. Chest. 2019;156(2):289–297. doi: 10.1016/j.chest.2019.03.032. - DOI - PMC - PubMed

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