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. 2025 Jul 25;17(15):2437.
doi: 10.3390/nu17152437.

Associations Between Maternal Meal Frequency Patterns During Pregnancy and Neonatal Anthropometric Outcomes: A Quantitative Cross-Sectional Study

Oana Liliana Atomei  1   2 , Petronela Vicoveanu  3   4 , Camelia Oana Iațcu  2 , Florina Ioana Gliga  5 , Calin Coriolan Craciun  6   7 , Monica Tarcea  8
Affiliations

Associations Between Maternal Meal Frequency Patterns During Pregnancy and Neonatal Anthropometric Outcomes: A Quantitative Cross-Sectional Study

Oana Liliana Atomei et al. Nutrients. .

Abstract

Background/Objectives: Maternal dietary behaviors, including meal frequency patterns, may influence fetal growth. This study examined the associations between maternal meal frequency patterns during pregnancy-categorized as structured, moderately irregular, or highly irregular-and neonatal anthropometric outcomes, including weight, length, head, chest, and abdominal circumferences, and Apgar score. A secondary objective was to assess whether maternal education and household income modify these associations. Methods: This cross-sectional study included 1025 mother-newborn pairs from a socioeconomically diverse Romanian cohort. Maternal meal frequency patterns were classified based on self-reported weekly consumption. Neonatal anthropometric outcomes were obtained from medical records. Multivariable linear regression models, adjusted for maternal and neonatal characteristics, assessed the associations between meal frequency patterns and birth outcomes. Interaction terms evaluated effect modification by maternal education and income. Results: Structured maternal meal frequency patterns were associated with a slight but significant reduction in neonatal length compared to highly irregular patterns (β = -0.36 cm; 95% CI: -0.68 to -0.04; p = 0.02). A borderline inverse association with birth weight was also observed (β = -63.82 g; 95% CI: -128.87 to 1.23; p = 0.05). No significant differences were found for other anthropometric indicators or Apgar score. Maternal education modified the association between moderately irregular patterns and chest circumference (β = 0.15 cm; 95% CI: 0.04 to 0.25; p = 0.003), while household income modified the association with abdominal circumference (β = 0.14 cm; 95% CI: 0.02 to 0.26; p = 0.02). Conclusions: Maternal meal frequency patterns were modestly associated with neonatal length, while socioeconomic factors modified specific anthropometric outcomes. These findings highlight the importance of considering social context in prenatal nutritional recommendations.

Keywords: birth weight; fetal growth; maternal nutrition; meal frequency; neonatal anthropometry; pregnancy; socioeconomic status.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

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Figure 1
Flow chart showing selection of study participants.
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References

    1. Adeoye I.A., Unogu C.O., Adediran K., Gbadebo B.M. Determinants of Adverse Perinatal Outcomes in Ibadan, Nigeria: The Influence of Maternal Lifestyle. PLoS Glob. Public Health. 2025;5:e0004199. doi: 10.1371/journal.pgph.0004199. - DOI - PMC - PubMed
    1. Magnano San Lio R., Barchitta M., Maugeri A., Campisi E., Favara G., Granados C.O., La Mastra C., La Rosa M.C., Galvani F., Pappalardo E., et al. Sex Differences in Delivery and Neonatal Characteristics of New-Borns from the “MAMI-MED” Cohort. Front. Public Health. 2025;13:1498125. doi: 10.3389/fpubh.2025.1498125. - DOI - PMC - PubMed
    1. Wrottesley S.V., Lamper C., Pisa P.T. Review of the Importance of Nutrition During the First 1000 Days: Maternal Nutritional Status and Its Associations with Fetal Growth and Birth, Neonatal and Infant Outcomes Among African Women. J. Dev. Orig. Health Dis. 2015;7:144–162. doi: 10.1017/S2040174415001439. - DOI - PubMed
    1. Rugină C., Mărginean C.O., Meliţ L.E., Giga D.V., Modi V., Mărginean C. Relationships Between Excessive Gestational Weight Gain and Energy and Macronutrient Intake in Pregnant Women. J. Int. Med. Res. 2020;48:8. doi: 10.1177/0300060520933808. - DOI - PMC - PubMed
    1. Iacob O.M., Bacârea A., Ruța F.D., Bacârea V.C., Gliga F.I., Buicu F., Tarcea M., Avram C., Costea G.C., Sin A.I. Anthropometric Indices of the Newborns Related with Some Lifestyle Parameters of Women during Pregnancy in Tirgu Mures Region—A Pilot Study. Prog. Nutr. 2018;20:585–591. doi: 10.23751/PN.V20I4.7080. - DOI

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