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Review
. 2025 Jul 29;14(15):2675.
doi: 10.3390/foods14152675.

Functional Foods in Clinical Trials and Future Research Directions

Zsuzsa Emma Hajzer  1 , Walaa Alibrahem  2 , Nihad Kharrat Helu  2 , Csaba Oláh  2   3   4 , József Prokisch  5
Affiliations
Review

Functional Foods in Clinical Trials and Future Research Directions

Zsuzsa Emma Hajzer et al. Foods. .

Abstract

Clinical trials serve as a cornerstone in the meticulous assessment of the efficacy and myriad health benefits that functional foods offer. These trials are not merely confined to the specific domain of functional foods; rather, they resonate throughout the expansive realms of nutrition science and public health, illuminating the intricate interdependencies that exist among these disciplines. This interconnectedness is becoming increasingly apparent, emphasizing the significant influence of scientific inquiry on fostering healthier dietary habits and shaping well-informed public health strategies. Functional food clinical trials yield essential insights into the potential of functional foods to enhance health outcomes, thereby playing a pivotal role in the prevention of various ailments and substantially elevating the quality of life for individuals in diverse contexts. By delivering consistent and compelling results, these trials bolster the foundational knowledge requisite healthcare practitioners to navigate dietary decisions wisely. Ultimately, the impact of such trials transcends individual health, contributing to the collective well-being of communities. They serve as a vital link between scientific progress and practical implementation, ensuring that the benefits of research are seamlessly integrated into everyday dietary practices, thereby promoting a healthier society at large.

Keywords: antioxidants; clinical trials; functional foods; omega-3 fatty acids; postbiotics; prebiotics; probiotics.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Chronological overview of functional food concept’s evolution.
Figure 2
Figure 2
Balancing functional food and chemical drugs.
See this image and copyright information in PMC

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