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Review
. 2025 Jul 30:19:1554147.
doi: 10.3389/fnhum.2025.1554147. eCollection 2025.

Aphasia rehabilitation: a narrative review of adjuvant techniques

Stacy M Harnish  1 , Courtney C Jewell  1 , Natalie G Freitag  1 , Grace E Terry  1 , Gillian I Anderson  1
Affiliations
Review

Aphasia rehabilitation: a narrative review of adjuvant techniques

Stacy M Harnish et al. Front Hum Neurosci. .

Abstract

Adjuvant techniques, or strategies that may be employed alongside language therapy for individuals with aphasia, are increasingly gaining attention for their ability to promote an enhanced brain environment for neuroplasticity. This narrative review describes active ingredients, mechanisms of action, potential modulating factors and evidence for efficacy of non-invasive brain stimulation techniques, such as transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS); aerobic exercise; intention treatment; and pharmacotherapies, including monoaminergic, cholinergic, glutaminergic, and nootropic medications that have been used in concert with language therapy for aphasia.

Keywords: adjuvant; aerobic exercise; aphasia; non-invasive brain stimulation (NIBS); pharmacotherapy; treatment.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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References

    1. Ali M., VandenBerg K., Williams L. J., Williams L. R., Abo M., Becker F., et al. (2021). Predictors of poststroke aphasia recovery. Stroke 52, 1778–1787. 10.1161/STROKEAHA.120.031162 - DOI - PMC - PubMed
    1. Allard J. S., Ntekim O., Johnson S. P., Ngwa J. S., Bond V., Pinder D., et al. (2017). APOEε4 impacts up-regulation of brain-derived neurotrophic factor after a six-month stretch and aerobic exercise intervention in mild cognitively impaired elderly African Americans: a pilot study. Exp. Gerontol. 87, 129–136. 10.1016/j.exger.2016.11.001 - DOI - PMC - PubMed
    1. Almeida M. B., Araújo C. G. S. (2003). Effects of aerobic training on heart rate. Rev. Bras. Med. Esporte 9, 113–120. 10.1590/S1517-86922003000200006 - DOI
    1. Altmann L. J. P., Hazamy A. A., Carvajal P. J., Benjamin M., Rosenbek J. C., Crosson B. (2014). Delayed stimulus-specific improvements in discourse following anomia treatment using an intentional gesture. J. Speech Lang. Hear. Res. 57, 439–454. 10.1044/1092-4388(2013/12-0224) - DOI - PMC - PubMed
    1. Ashtary F., Janghorbani M., Chitsaz A., Reisi M., Bahrami A. (2006). A randomized, double-blind trial of bromocriptine efficacy in nonfluent aphasia after stroke. Neurology 66, 914–916. 10.1212/01.wnl.0000203119.91762.0c - DOI - PubMed

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