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Review
. 2025 Jul 31;17(7):357-364.
doi: 10.14740/jocmr6276. eCollection 2025 Jul.

Association of ABO and Rhesus Blood Groups With Oral Cancers

Khaldun Jacoub  1 , Ali Abdelfattah  1   2
Affiliations
Review

Association of ABO and Rhesus Blood Groups With Oral Cancers

Khaldun Jacoub et al. J Clin Med Res. .

Abstract

The ABO and Rhesus blood systems have been studied extensively in relation to various diseases, including cancers. Recent evidence suggests that ABO blood group may influence susceptibility to oral potentially malignant disorders (OPMDs) and oral cancers, particularly oral squamous cell carcinoma (OSCC). The current review explores the association of ABO and Rhesus blood groups with oral cancers, summarizing epidemiological, molecular, and immunological studies to elucidate potential mechanisms underlying this relationship.

Keywords: ABO blood group; Oral cancers; Oral potentially malignant disorders; Rhesus blood groups.

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Conflict of interest statement

The authors declare no conflict of interest.

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