Editorial: Use of quantitative systems pharmacology pipelines to bridge in vitro and in vivo results in drug discovery
- PMID: 40809493
- PMCID: PMC12342030
- DOI: 10.3389/fsysb.2023.1291610
Editorial: Use of quantitative systems pharmacology pipelines to bridge in vitro and in vivo results in drug discovery
Keywords: artificial intelligence; chemical reaction networks (CRNs); drug discovery; mathematical modelling; mechanism of action (MOA); model informed drug development; quantitative systems pharmacology (QSP).
Conflict of interest statement
Author AC-N was employed by Cytocast Hungary Kft. Author GS was employed by Pharmetheus AB. The remaining author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The authors declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision
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- Editorial on the Research Topic Use of quantitative systems pharmacology pipelines to bridge in vitro and in vivo results in drug discovery
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References
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- Sorger P. K., Sorger P. K., Allerheiligen S. R., Abernethy D. R., Altman R. B., Brouwer K. L., et al. (2011). “Quantitative and systems pharmacology in the post-genomic era: new approaches to discovering drugs and understanding therapeutic mechanisms,” in An NIH white paper by the QSP workshop group (Bethesda, MD: NIH; ), 48, 1–47.
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