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Editorial
. 2025 Aug 14;146(7):774-775.
doi: 10.1182/blood.2025029478.

Giving ALL a SMAC down (and HDAC down) towards cell death

Sarah K Tasian  1   2   3
Affiliations
Editorial

Giving ALL a SMAC down (and HDAC down) towards cell death

Sarah K Tasian. Blood. .
No abstract available

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Conflict of interest statement

Conflict-of-interest disclosure: The author declares no competing financial interests.

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References

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    1. Raetz EA, Bhojwani D, Devidas M, et al. Children's Oncology Group blueprint for research: acute lymphoblastic leukemia. Pediatr Blood Cancer. 2023;70(suppl 6) - PMC - PubMed
    1. Gupta S, Rau RE, Kairalla JA, et al. Blinatumomab in standard-risk B-cell acute lymphoblastic leukemia in children. N Engl J Med. 2025;392(9):875–891. - PMC - PubMed
    1. Gibson A, Trabal A, McCall D, et al. Venetoclax for children and adolescents with acute lymphoblastic leukemia and lymphoblastic lymphoma. Cancers (Basel) 2021;14(1) - PMC - PubMed
    1. McComb S, Aguadé-Gorgorió J, Harder L, et al. Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL. Sci Transl Med. 2016;8(339):339ra370. - PubMed

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