doi: 10.1007/BF01946005.
A facile one-step synthesis of cysteinyldopas using mushroom tyrosinase
- PMID: 408183
- DOI: 10.1007/BF01946005
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A facile one-step synthesis of cysteinyldopas using mushroom tyrosinase
Experientia.
.
Abstract
A convenient one-step procedure, based upon the tyrosinase co-oxidation of dopa and cysteine, is reported for the synthesis of 5-S-cysteinyldopa (I) in 74% yield. Secondary products of the reaction turned out to be 2-S-cysteinyldopa (II, 14%), 2,5-S, S-dicysteinyldopa (iv, 5%), and the hitherto unknown 6-S-cysteinyldopa (III, approximately 1%).
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