Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2025 Jul 15;17(7):5214-5220.
doi: 10.62347/UMOA1809. eCollection 2025.

Anesthetic management of diabetic foot amputation in a patient with renal failure and maintenance hemodialysis: case report and short communication

Affiliations
Case Reports

Anesthetic management of diabetic foot amputation in a patient with renal failure and maintenance hemodialysis: case report and short communication

Meng-Hao Wu et al. Am J Transl Res. .

Abstract

Chronic kidney disease (CKD) can progress to an advanced stage, eventually developing into end-stage renal disease (ESRD). Currently, the only effective treatment for ESRD is renal replacement therapy, with maintenance hemodialysis (MHD) being the most widely used modality, accounting for approximately 90% of all dialysis patients. However, the perioperative risk of surgery and anesthesia in these patients remains extremely high. Therefore, careful selection of surgical timing, appropriate anesthetic agents, and suitable anesthetic techniques is crucial. This report describes the anesthetic management of a 62-year-old female patient who had been hospitalized in the orthopedic ward for nine months due to left toe necrosis secondary to diabetic foot, in the setting of CKD requiring MHD. She was later admitted to Xingtai Central Hospital with progressive necrosis involving the left second and third toes and extending to the dorsum and plantar aspect of the foot. The patient was diagnosed with left-sided diabetic foot necrosis, stage 5 CKD, type 2 diabetes mellitus with multiple complications, grade 3 hypertension (high risk), and chronic hepatitis B infection. An elective transtibial (below-knee) amputation of the left lower limb was planned. Anesthesia was provided using color Doppler ultrasound-guided left iliac fascia block, left lateral femoral cutaneous nerve block, and left sciatic nerve block. Intravenous isoproterenol infusion, dexmedetomidine, and dizocine injection were administered for intraoperative sedation and analgesia. The patient's intraoperative vital signs remained stable. Postoperatively, the patient was awake, in good general condition, and was transferred to the ward with regular monitoring.

Keywords: Renal failure; anesthesia management; maintenance hemodialysis; surgery.

PubMed Disclaimer

Conflict of interest statement

None.

Figures

Figure 1
Figure 1
Radiographic image of the patient. A: Chest X-ray; B: Cardiac ultrasound; C: Arteriovenous ultrasound.

Similar articles

References

    1. Yang L, He Y, Li X. Physical function and all-cause mortality in patients with chronic kidney disease and end-stage renal disease: a systematic review and meta-analysis. Int Urol Nephrol. 2023;55:1219–1228. - PubMed
    1. Lin MY, Liu MF, Hsu LF, Tsai PS. Effects of self-management on chronic kidney disease: a meta-analysis. Int J Nurs Stud. 2017;74:128–137. - PubMed
    1. Yu IC, Tsai YF, Fang JT, Yeh MM, Fang JY, Liu CY. Effects of mouthwash interventions on xerostomia and unstimulated whole saliva flow rate among hemodialysis patients: a randomized controlled study. Int J Nurs Stud. 2016;63:9–17. - PubMed
    1. Wald R, Beaubien-Souligny W, Chanchlani R, Clark EG, Neyra JA, Ostermann M, Silver SA, Vaara S, Zarbock A, Bagshaw SM. Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury. Intensive Care Med. 2022;48:1368–1381. - PubMed
    1. Wong SPY, Rubenzik T, Zelnick L, Davison SN, Louden D, Oestreich T, Jennerich AL. Long-term outcomes among patients with advanced kidney disease who forgo maintenance dialysis: a systematic review. JAMA Netw Open. 2022;5:e222255. - PMC - PubMed

Publication types

LinkOut - more resources