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Case Reports
. 2025 Aug 7:2025:9368865.
doi: 10.1155/crot/9368865. eCollection 2025.

Chondroblastoma Located in the Anterior Skull Base: A Case Report and Comprehensive Literature Review

Mohsen Fazli  1 , Mahdi Khajavi  1 , Sara Mohammadi  2 , Amir Zaker  1 , Mohammad Jalili  1 , Farzin Davoodi  1 , Narges Bazgir  1 , Nader Akbari  1
Affiliations
Case Reports

Chondroblastoma Located in the Anterior Skull Base: A Case Report and Comprehensive Literature Review

Mohsen Fazli et al. Case Rep Otolaryngol. .

Abstract

Background: Chondroblastoma is a rare and benign bone tumor originating from immature chondroblasts. Chondroblastoma typically affects long bones; however, it can also occur in the skull, especially the temporal bone. The anterior skull base is a rare location for this tumor, with only two reported cases. Case Presentation: A 26-year-old woman presented with epiphora in her right eye and progressive proptosis on the same side. She had a previous biopsy that confirmed the presence of a giant cell tumor of the bone and had undergone an unsuccessful endoscopic surgery. A comprehensive endoscopic procedure subsequently revealed a cartilage-producing neoplasm consistent with chondroblastoma. Conclusion: We presented a successful case of surgical resection of a chondroblastoma in the anterior skull base. Additionally, we reviewed the existing literature and previously documented cases.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
The CT (a) and T1-weighted MRI (b) of the patient before surgery.
Figure 2
Figure 2
The T2-weighted MRI of presented case.
Figure 3
Figure 3
The findings of pathological investigations. The pathology revealed a cartilage-producing tumor with various magnifications. (a) Hematoxylin and eosin ×40 and (b) hematoxylin and eosin ×100.
Figure 4
Figure 4
The patient's postoperative CT scan after a year.
See this image and copyright information in PMC

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