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. 2025 Aug 15;38(3):209-216.
doi: 10.2337/dsi25-0004. eCollection 2025 Summer.

Dosing Algorithms for Insulin Pumps

Ali Cinar  1
Affiliations

Dosing Algorithms for Insulin Pumps

Ali Cinar. Diabetes Spectr. .

Abstract

Advances in insulin pumps and dosing algorithms have improved the regulation of blood glucose concentrations, reduced the frequency of hyperglycemic and hypoglycemic episodes, and improved quality of life for people with diabetes and their families. Whereas nonautomated or standard insulin pumps may work with a smartphone app to provide information to reduce the workload of users, major advances have been made in automated insulin delivery (AID) system pumps that adjust insulin infusion rates via proprietary algorithms in real time based on data from a continuous glucose monitoring sensor that communicates with the AID pump to take over additional tasks. Improvements in these algorithms are reducing the burden on users today, while the next generation of AID systems, with full automation, are under development.

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Conflict of interest statement

The author’s multivariable AID research is supported by the National Institutes of Health under grants 1DP3DK101077, 1DP3DK101075, 1R01DK130049, and R01DK135116 and by Breakthrough T1D under grants 17-2013-472 and 2-SRA-2017-506-M-B.

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