Immunochemical investigations of human pituitary beta-lipotropin
- PMID: 408288
- DOI: 10.1111/j.1399-3011.1977.tb02791.x
Immunochemical investigations of human pituitary beta-lipotropin
Abstract
Antiserum to human beta-lipotropin has been raised in rabbits and characterized by gel double diffusion, quantitative precipitin, microcomplement fixation and biological neutralization tests. A sensitive radioimmunoassay for human beta-lipotropin has been developed. It was demonstrated that the antiserum shows specificity for this hormone. Human beta-melanotropin and human beta-endorphin showed only a minimal degree of cross-reaction, while ovine beta-lipotropin showed a partial but significant degree of cross-reactivity.
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