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. 2025 Aug 19;25(1):477.
doi: 10.1186/s12886-025-04308-0.

Evaluation by M-charts and Microperimeter-MP3 after broad internal limiting membrane peeling for idiopathic epiretinal membrane

Naoto Uchiyama  1 , Tatsuya Jujo  2 , Keiji Sato  1 , Reio Sekine  1 , Kota Kakehashi  1 , Akiko Endo  1 , Yasushi Kitaoka  1
Affiliations

Evaluation by M-charts and Microperimeter-MP3 after broad internal limiting membrane peeling for idiopathic epiretinal membrane

Naoto Uchiyama et al. BMC Ophthalmol. .

Abstract

Purpose: To assess the impact of broad-internal limiting membrane (ILM) peeling on retinal sensitivity (RS) and metamorphopsia assessed using M-CHARTS in patients with idiopathic epiretinal membrane (ERM).

Design: Retrospective observational case series.

Methods: The study analyzed 20 eyes treated with broad-ILM peeling within the vascular arcades area for ERM, over a 6-month follow-up. Outcomes measured included best-corrected visual acuity (BCVA), vertical M-CHARTS scores(MV) and horizontal M-CHARTS scores (MV), central macular thickness (CMT), and RS. RS was evaluated using Microperimeter-MP3 at specified central degrees, and points below 10 dB were considered microscotomas (MS).

Results: Postoperative BCVA improved significantly at 1 month, 3 months, and 6 months(all p < 0.01).No significant changes in CMT were noted.MH score improvements were significant at 6 months (P = 0.03), whereas MV scores remained unchanged (P > 0.05).RS notably improved within the central 4° at 3 months (P = 0.04) and 6 months (P = 0.05), but remained unchanged in the central 10° and 20° regions (P > 0.05).

MS did not increase significantly at 1 month postoperatively and remained stable through 3 and 6 months (all P > 0.05).

Conclusion: Broad ILM peeling suggests potential for improving visual acuity and metamorphopsia in ERM patients without causing long-term detrimental effects on retinal sensitivity or increasing the occurrence of MS.

Supplementary Information: The online version contains supplementary material available at 10.1186/s12886-025-04308-0.

Keywords: Broad peeling; Epiretinal membrane; Internal limiting membrane; Microperimeter; Microscotomas; Retinal sensitivity.

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: The study was conducted in accordance with the Declaration of Helsinki, and approved by the Ethics Committee of St. Marianna University School of Medicine (Approval No. 5477, 26 November 2021). Written informed consent was obtained from all patients prior to surgery. This included consent to undergo the surgical procedure as well as permission for the use of postoperative clinical data for research purposes by the institution. To ensure patient autonomy, information regarding the study objectives and period was disclosed via an opt-out document made publicly available. This allowed patients who had previously provided consent to withdraw from participation if they so wished. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
MP-3 screen measured 32 spots within 20. Measurements were taken at 32 points within a central range of 20°. This measurement range was set to evaluate the Broad ILM Peeling (peeling range within the vascular arcade) area. Sensitivity was defined as measurement points with less than 10 dB, and the data was recorded appropriately
Fig. 2
Fig. 2
The area of four regions. The area was divided into four regions, nasal (point N1–8), superior (point S1–8), temporal (point T1–8), and inferior (point I1–8)
See this image and copyright information in PMC

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