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Review
. 2025 Sep;52(3):471-485.
doi: 10.1016/j.pop.2025.05.001. Epub 2025 Jul 4.

Comprehensive Management of Skin Infections in Primary Care: Diagnosis, Treatment, and Evidence-Based Recommendations

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Review

Comprehensive Management of Skin Infections in Primary Care: Diagnosis, Treatment, and Evidence-Based Recommendations

Karl T Clebak et al. Prim Care. 2025 Sep.

Abstract

Skin infections are prevalent in primary care, spanning from superficial conditions like impetigo to severe, life-threatening cases such as necrotizing fasciitis. This article provides an in-depth review of the clinical presentation, diagnosis, and management of common bacterial, fungal, and viral skin infections, with practical insights tailored for primary care physicians. Emphasis is placed on evidence-based approaches, distinguishing features between similar infections, and treatment options ranging from topical antibiotics to advanced surgical interventions. This comprehensive guide ensures primary care providers are equipped to recognize and manage skin infections effectively, enhancing patient outcomes through timely and appropriate care.

Keywords: Bacterial skin diseases; Dermatomycoses; Infectious skin diseases; Viral skin diseases.

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Conflict of interest statement

Disclosure The authors declare that they have no conflicts of interest related to this publication.

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