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. 2025 Sep 11;61(74):14197-14200.
doi: 10.1039/d5cc02827b.

Glycan-induced fluorescence enhancement using a molecular rotor-boronic acid conjugate

Mandana Oloub  1 , Alen Koçak  1 , Cihan Baydaroğlu  2 , Amal K Homer  1 , Florian Telschow  3 , Victor M Loyo-Cruz  3 , Sebastian Trunschke  1 , Gaël M Vos  4 , Kevin Pagel  4 , Michael Gradzielski  2 , Ulrike Alexiev  3 , Oliver Seitz  1
Affiliations

Glycan-induced fluorescence enhancement using a molecular rotor-boronic acid conjugate

Mandana Oloub et al. Chem Commun (Camb). .

Abstract

Fluorescent molecular rotors (FMRs) are known for their sensitivity to changes in viscosity and confinement. Here, we show that a boronic acid conjugate of the rotor dye CCVJ exhibits strong enhancements in fluorescence upon binding to complex glycans. Glycan-induced fluorescence enhancement (GIFE) operates at low and high viscosity.

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