Malignant gastric outlet obstruction: The emerging role of endoscopic ultrasound-guided gastroenterostomy

Abstract

Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is emerging as a preferred approach for managing malignant gastric outlet obstruction. This technique offers a balance between the durability of surgical gastrojejunostomy (SGJ) and the minimally invasive nature of endoscopic methods. Compared to enteral stenting, EUS-GE shows superior outcomes, including higher long-term patency, lower symptom recurrence, and fewer reinterventions. It also demonstrates comparable or better efficacy than SGJ, with faster oral intake, shorter hospital stays, and reduced complications. However, EUS-GE requires specialized expertise, and long-term outcome data remain limited, so further research is needed to refine protocols and optimize patient selection.

Keywords: Endoscopic ultrasound; Endoscopy; Gastric outlet obstruction; Gastrojejunostomy; Interventional; Malignant gastroenterostomy.