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. 1985 Oct;50(4):1115-7.
doi: 10.1128/aem.50.4.1115-1117.1985.

Comparison of animal infectivity and excystation as measures of Giardia muris cyst inactivation by chlorine

J C Hoff, E W Rice, F W Schaefer 3rd

Comparison of animal infectivity and excystation as measures of Giardia muris cyst inactivation by chlorine

J C Hoff et al. Appl Environ Microbiol. 1985 Oct.

Abstract

In this study, in vitro excystation and mouse infectivity were compared as methods for quantitatively determining the viability of Giardia muris cysts before and after exposure to free residual chlorine. The mouse infectivity results show that very few cysts (1 to 15) constitute an infectious dose. The results of the inactivation studies indicate that in vitro excystation is an adequate indication of G. muris cyst infectivity for the host and can be used to determine the effects of disinfectants on cyst viability.

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