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Review
. 2025 Aug 21;300(1):77.
doi: 10.1007/s00438-025-02283-1.

Role of Php domain and related enzymes in the enzymatic degradation of G-series nerve agents

Divya Ramamoorthy  1 , Rupa Iyer  2
Affiliations
Review

Role of Php domain and related enzymes in the enzymatic degradation of G-series nerve agents

Divya Ramamoorthy et al. Mol Genet Genomics. .
No abstract available

Keywords: Bacterial strains; Enzyme degradation; G-nerve agents; Organophosphates; Pesticides.

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Conflict of interest statement

Declarations. Conflict of interest: The authors declare no conflict of interest.

References

    1. Aharoni A, Gaidukov L, Yagur S, Toker L, Silman I, Tawfik DS (2004) Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization. Proc Natl Acad Sci U S A 101(2):482–487. https://doi.org/10.1073/pnas.2536901100 - DOI - PubMed
    1. Anderson DW, Baier F, Yang G, Tokuriki N (2021) The adaptive landscape of a metallo-enzyme is shaped by environment-dependent epistasis. Nat Commun 12(1):3867. https://doi.org/10.1038/s41467-021-23943-x From NLM - DOI - PubMed - PMC
    1. Awasthi S, Chauhan R, Dwivedi S, Srivastava S, Srivastava S, Tripathi RD (2018) A consortium of Alga (Chlorella vulgaris) and bacterium (Pseudomonas putida) for amelioration of arsenic toxicity in rice: a promising and feasible approach. Environ Exp Bot 150:115–126. https://doi.org/10.1016/j.envexpbot.2018.03.001 - DOI
    1. Bigley AN, Raushel FM (2013) Catalytic mechanisms for phosphotriesterases. Biochim Biophys Acta 1834(1):443–453. https://doi.org/10.1016/j.bbapap.2012.04.004 - DOI - PubMed
    1. Carletti E, Jacquamet L, Loiodice M, Rochu D, Masson P, Nachon F (2009) Update on biochemical properties of recombinant Pseudomonas diminuta phosphotriesterase. J Enzyme Inhib Med Chem 24(4):1045–1055. https://doi.org/10.1080/14756360802608518 - DOI - PubMed

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