A protein tunnel helps stressed lysosomes swell
- PMID: 40839749
- DOI: 10.1126/science.aea5377
A protein tunnel helps stressed lysosomes swell
Abstract
The endoplasmic reticulum donates lipids through a tunnel-like protein to help lysosomes expand.
Comment on
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LYVAC/PDZD8 is a lysosomal vacuolator.Science. 2025 Aug 21;389(6762):eadz0972. doi: 10.1126/science.adz0972. Epub 2025 Aug 21. Science. 2025. PMID: 40839735 Free PMC article.
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