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Review
. 2025 Aug 19:S0039-6257(25)00142-0.
doi: 10.1016/j.survophthal.2025.08.011. Online ahead of print.

Silicone oil removal-related vision loss

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Free article
Review

Silicone oil removal-related vision loss

Maria Ludovica Ruggeri et al. Surv Ophthalmol. .
Free article

Abstract

Silicone oil removal-related vision loss (SORVL) is a sight-threatening condition affecting a small fraction of patients after the removal of silicone oil, possibly underestimated. To date, a few cases have been thoroughly investigated; however, no clear and unique explanation has been found for this phenomenon. Most of the literature has been focusing on SORVL and in situ SORVL, gathering the 2 conditions under the same pathogenic mechanism. In this review, we provide a detailed update on SORVL describing its epidemiology and the reported signs and symptoms. Furthermore, we explore possible underlying mechanisms that may contribute to the development of SORVL giving insights into the pathophysiology of this rare and severe condition.

Keywords: Pars Plana Vitrectomy; Retinal detachment surgery; Silicone Oil; Silicone oil removal related vision loss; Unexplained vision loss; Vitreoretinal surgery.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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