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Case Reports
. 2025 Sep 1;57(5):356-358.
doi: 10.4103/ijp.ijp_134_25. Epub 2025 Aug 22.

Bleomycin-induced Sweet's syndrome

Anuja Yadav  1 , Vishal Gaurav, Deepika Yadav, Sonika Garg
Affiliations
Case Reports

Bleomycin-induced Sweet's syndrome

Anuja Yadav et al. Indian J Pharmacol. .

Abstract

Sweet's syndrome is also called as acute febrile neutrophilic dermatosis. Drug-induced Sweet's syndrome was first reported in association with trimethoprim-sulfamethoxazole. It is very rare. To the best of our knowledge, bleomycin-induced Sweet's syndrome has not been reported previously.

Keywords: Bleomycin; Sweet’ syndrome; chemotherapy.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Multiple discrete well defined to ill-defined erythematous plaques with flagellate morphology presentover (a) left thigh; (b) right infra-mammary area; and (c) upper part of left leg
Figure 2
Figure 2
Microphotographs showing (a) mild spongiosis and flattening of rete ridges, moderate dermal edema (H and E, 40X); and (b) a diffuse dermal inflammatory infiltrate composed predominantly of neutrophils, few lymphocytes, histocytes, and neutrophilic leukocytoclasia (H and E; 400x)
See this image and copyright information in PMC

References

    1. Yamamoto T. Bleomycin and the skin. Br J Dermatol. 2006;155:869–75. - PubMed
    1. Cohen IS, Mosher MB, O’Keefe EJ, Klaus SN, De Conti RC. Cutaneous toxicity of bleomycin therapy. Arch Dermatol. 1973;107:553–5. - PubMed
    1. Walker DC, Cohen PR. Trimethoprim-sulfamethoxazole-associated acute febrile neutrophilic dermatosis: Case report and review of drug-induced Sweet’s syndrome. J Am Acad Dermatol. 1996;34:918–23. - PubMed
    1. Cohen PR, Kurzrock R. Sweet’s syndrome and cancer. Clin Dermatol. 1993;11:149–57. - PubMed
    1. Cohen PR, Kurzrock R. Treatment of Sweet’s syndrome. Am J Med. 1990;89:396. - PubMed

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