Cardiopulmonary exercise testing unmasks right ventricular failure in pulmonary arterial hypertension risk stratification: time to reframe the role of the 6-minute walk test?

Andrew Constantine¹, Konstantinos Dimopoulos^{2

3

4}, Colm McCabe³

Affiliations

¹ Adult Congenital Heart Disease Unit, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
² Adult Congenital Heart Centre, Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK k.dimopoulos02@gmail.com.
³ National Pulmonary Hypertension Centre, Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
⁴ National Heart and Lung Institute, Imperial College London, London, UK.

Editorial

Andrew Constantine et al. Eur Respir J. 2025.

. 2025 Aug 22;66(2):2500849.

doi: 10.1183/13993003.00849-2025. Print 2025 Aug.

Andrew Constantine¹, Konstantinos Dimopoulos^{2

3

4}, Colm McCabe³

¹ Adult Congenital Heart Disease Unit, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
² Adult Congenital Heart Centre, Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK k.dimopoulos02@gmail.com.
³ National Pulmonary Hypertension Centre, Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
⁴ National Heart and Lung Institute, Imperial College London, London, UK.

No abstract available

Conflict of interest statement

Conflict of interest: The authors have no potential conflicts of interest to disclose.

Prognostic value of cardiopulmonary exercise testing in pulmonary arterial hypertension.
Baccelli A, Rinaldo RF, Haji G, Davies RJ, Lo Giudice F, Gin-Sing W, Vigo B, Centanni S, Gibbs JSR, Howard LS. Baccelli A, et al. Eur Respir J. 2025 Aug 22;66(2):2402026. doi: 10.1183/13993003.02026-2024. Print 2025 Aug. Eur Respir J. 2025. PMID: 40210410 Free PMC article.