Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Aug 23.
doi: 10.1007/s00330-025-11947-w. Online ahead of print.

Diagnostic value of artificial intelligence-based software for the detection of pediatric upper extremity fractures

Affiliations

Diagnostic value of artificial intelligence-based software for the detection of pediatric upper extremity fractures

Federico Mollica et al. Eur Radiol. .

Abstract

Objectives: Fractures in children are common in emergency care, and accurate diagnosis is crucial to avoid complications affecting skeletal development. Limited access to pediatric radiology specialists emphasizes the potential of artificial intelligence (AI)-based diagnostic tools. This study evaluates the performance of the AI software BoneView® for detecting fractures of the upper extremity in children aged 2-18 years.

Materials and methods: A retrospective analysis was conducted using radiographic data from 826 pediatric patients presenting to the university's pediatric emergency department. Independent assessments by two experienced pediatric radiologists served as reference standard. The diagnostic accuracy of the AI tool compared to the reference standard was evaluated and performance parameters, e.g., sensitivity, specificity, positive and negative predictive values were calculated.

Results: The AI tool achieved an overall sensitivity of 89% and specificity of 91% for detecting fractures of the upper extremities. Significantly poorer performance compared to the reference standard was observed for the shoulder, elbow, hand, and fingers, while no significant difference was found for the wrist, clavicle, upper arm, and forearm. The software performed best for wrist fractures (sensitivity: 96%; specificity: 94%) and worst for elbow fractures (sensitivity: 87%; specificity: 65%).

Conclusion: The software assessed provides diagnostic support in pediatric emergency radiology. While its overall performance is robust, limitations in specific anatomical regions underscore the need for further training of the underlying algorithms. The results suggest that AI can complement clinical expertise but should not replace radiological assessment.

Key points: Question There is no comprehensive analysis of an AI-based tool for the diagnosis of pediatric fractures focusing on the upper extremities. Findings The AI-based software demonstrated solid overall diagnostic accuracy in the detection of upper limb fractures in children, with performance differing by anatomical region. Clinical relevance AI-based fracture detection can support pediatric emergency radiology, especially where expert interpretation is limited. However, further algorithm training is needed for certain anatomical regions and for detecting associated findings such as joint effusions to maximize clinical benefit.

Keywords: Deep learning; Fracture; Machine learning; Pediatric; Radiograph.

PubMed Disclaimer

Conflict of interest statement

Compliance with ethical standards. Guarantor: The scientific guarantor of this publication is Simon Veldhoen. Conflict of interest: The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article. Statistics and biometry: No complex statistical methods were necessary for this paper. Informed consent: Written informed consent was waived by the Institutional Review Board. Ethical approval: Institutional Review Board approval was obtained. Study subjects or cohorts overlap: None of the study subjects or cohorts has been previously reported. Methodology: Retrospective Observational Performed at one institution

Similar articles

References

    1. Monget F, Sapienza M, McCracken KL et al (2022) Clinical characteristics and distribution of pediatric fractures at a tertiary hospital in Northern France: a 20-year-distance comparative analysis (1999–2019). Medicina (Kaunas) 58:610
    1. Jung HS, Park MS, Lee KM, Choi KJ, Choi WY, Sung KH (2021) Growth arrest and its risk factors after physeal fracture of the distal tibia in children and adolescents. Injury 52:844–848 - PubMed
    1. Hooper N, Johnson L, Banting N et al (2024) Risk factor analysis for growth arrest in paediatric physeal fractures—a prospective study. J Clin Med 13:2946
    1. Granata C, Sofia C, Francavilla M et al (2025) Let’s talk about radiation dose and radiation protection in children. Pediatr Radiol 55:386–396
    1. Altmann-Schneider I, Kellenberger CJ, Pistorius S-M et al (2024) Artificial intelligence-based detection of paediatric appendicular skeletal fractures: performance and limitations for common fracture types and locations. Pediat Radiol 54:136–145 - PubMed

LinkOut - more resources