Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jul;19(2):25-30.
doi: 10.5704/MOJ.2507.004.

Arthroscopic Osteochondral Autograft Transplantation (OAT) in Patients with Focal Osteochondral/Chondral Lesions of the Knee Mid-Term Clinical Outcome

Affiliations

Arthroscopic Osteochondral Autograft Transplantation (OAT) in Patients with Focal Osteochondral/Chondral Lesions of the Knee Mid-Term Clinical Outcome

N Mehta et al. Malays Orthop J. 2025 Jul.

Abstract

Introduction: Articular cartilage has limited healing potential as it is a hypocellular and avascular structure, hence it is to manage articular cartilage defects. The arthroscopic osteochondral autograft transplantation procedure is minimally invasive and cosmetically acceptable procedure to manage cartilage defects.

Materials and methods: This is a prospective study extending from 2018 to 2023 done at Sports Injury Center, New Delhi involving 36 patients with focal full-thickness chondral/osteochondral defect, age <45 were included. Global Chondral change, Multi ligamentous injuries, varus or valgus malalignment, kissing lesion and defect > 20mm were excluded. The osteochondral lesion was debrided down till healthy cartilage margins, donor graft was harvested from the non-weight-bearing area of the MFC. Lysholm score was used to assess functional outcome.

Results: Median age 35 years (range 20 - 44 years). A total of 51% of the patients were aged between 31 and 40 years (n=18). Male to female ratio was 3.37:1. The median defect size was 8mm (range 7-10mm). There was a gradual improvement in knee-specific symptoms with time. There was a significant increase in Lysholm score with time (p<0.0001).

Conclusion: The OATS procedure is a reliable, reproducible method and its results are encouraging with early mid-term follow-up; however, a long-term follow-up study is required to ascertain the validation of OATS procedure for preventing degenerative arthritis in patients with osteochondral injuries of the knee.

Keywords: focal osteochondral lesion; knee chondral lesion; osteochondral autograft transplantation (OAT).

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Fig. 1:
Fig. 1:
Arthroscopic image showing osteochondral defect filled using OAT Plug.

Similar articles

References

    1. Hadley CJ, Shi WJ, Murphy H, Tjoumakaris FP, Salvo JP, Freedman KB. The Clinical Evidence Behind Biologic Therapies Promoted at Annual Orthopaedic Meetings: A Systematic Review. Arthroscopy. 2019;35(1):251–9. doi: 10.1016/j.arthro.2018.05.037. doi: - DOI - PubMed
    1. Gowd AK, Cvetanovich GL, Liu JN, Christian DR, Cabarcas BC, Redondo ML et al. Management of Chondral Lesions of the Knee: Analysis of Trends and Short-Term Complications Using the National Surgical Quality Improvement Program Database. Arthroscopy. 2019;35(1):138–46. doi: 10.1016/j.arthro.2018.07.049. doi: - DOI - PubMed
    1. Fice MP, Miller JC, Christian R, Hannon CP, Smyth N, Murawski CD et al. The Role of Platelet-Rich Plasma in Cartilage Pathology: An Updated Systematic Review of the Basic Science Evidence. Arthroscopy. 2019;35(3):961–76.e3.. doi: 10.1016/j.arthro.2018.10.125. doi: - DOI - PubMed
    1. Berlet GC, Mascia A, Miniaci A. Treatment of unstable osteochondritis dissecans lesions of the knee using autogenous osteochondral grafts (mosaicplasty). Arthroscopy. 1999;5(3):312–6. doi: 10.1016/s0749-8063(99)70041-1. doi: - DOI - PubMed
    1. Hangody L, Vásárhelyi G, Hangody LR, Sükösd Z, Tibay G, Bartha L et al. Autologous osteochondral grafting--technique and long-term results. Injury. 2008;39 Suppl 1:S32–9. doi: 10.1016/j.injury.2008.01.041. doi: - DOI - PubMed

LinkOut - more resources