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. 1985 Nov;40(11):833-44.

[New derivatives of clofibrate and probucol. Preliminary study of their hypolipemic activity]

[Article in Italian]
P de Meglio, F Ravenna, S Manzardo, P Gentili, M Riva
  • PMID: 4085644

[New derivatives of clofibrate and probucol. Preliminary study of their hypolipemic activity]

[Article in Italian]
P de Meglio et al. Farmaco Sci. 1985 Nov.

Abstract

The preparation is reported of compounds with a free or esterified hydroxyisobutyric acid grouping characteristic of clofibrate, on various supporting molecules related to clofibrate itself or to probucol. Some compounds showed clear hypolipemic activity and for one compound (MG 6893) the effect was not accompanied by hepatomegalia.

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