Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2025 Aug 26.
doi: 10.1007/s00270-025-04148-x. Online ahead of print.

Comment on "Prognostic Performance of Model for End-Stage Liver Disease (MELD) 3.0 for Transjugular Intrahepatic Portosystemic Shunt (TIPS) Creation"

Affiliations
Editorial

Comment on "Prognostic Performance of Model for End-Stage Liver Disease (MELD) 3.0 for Transjugular Intrahepatic Portosystemic Shunt (TIPS) Creation"

Tanjima Tarique Laskar et al. Cardiovasc Intervent Radiol. .

Abstract

Michimoto et al. demonstrated superior prognostic performance of MELD 3.0 for elective TIPS. While findings support improved risk stratification, lack of data on patients not undergoing TIPS and exclusion of key clinical outcomes limit immediate applicability. Broader validation and inclusion of post-TIPS complications are needed to guide patient selection and treatment decisions effectively.

Keywords: Hepatic decompensation; Liver cirrhosis; Portal hypertension; Risk stratification; Transjugular intrahepatic portosystemic shunt.

PubMed Disclaimer

Conflict of interest statement

Declarations. Conflict of interest: The authors declare no financial interest relevant to this study. The authors declare no non-financial interests relevant to this study. Clinical Trial Registration Details/Number: Not applicable, as this study did not report a clinical trial. Ethical Approval: Not required. Generative AI Use Statement: Generative AI tools, including Paperpal and ChatGPT-4o, were utilized solely for language refinement, grammar enhancement, and stylistic refinement. These tools had no role in the conceptualization, data analysis, interpretation of the results, or substantive content development of this manuscript. All intellectual contributions, data analyses, and scientific interpretations were the sole work of the authors. The final content was critically reviewed and edited to ensure its accuracy and originality. The authors take full responsibility for the accuracy, originality, and integrity of the work. Human Ethics and Consent to Participate: Not applicable as no patient data were collected or analyzed in this commentary. Research Registry Number: Not applicable.

References

    1. Michimoto K, Campos L, Cushen S, Suzuki T, Yamada K, Naugler W, Farsad K. Prognostic performance of Model for End-Stage Liver Disease (MELD) 3.0 for transjugular intrahepatic portosystemic shunt (TIPS) creation. Cardiovasc Intervent Radiol. 2025. https://doi.org/10.1007/s00270-025-04116-5 . - DOI - PubMed
    1. Song J, Wang X, Yan Y, Xiang T, Luo X. MELD 3.0 score for predicting survival in patients with cirrhosis after transjugular intrahepatic portosystemic shunt creation. Dig Dis Sci. 2023;68(7):3185–92. https://doi.org/10.1007/s10620-023-07834-3 . - DOI - PubMed
    1. Kim WR, Mannalithara A, Heimbach JK, Kamath PS, Asrani SK, Biggins SW, Wood NL, Gentry SE, Kwong AJ. MELD 3.0: the model for end-stage liver disease updated for the modern era. Gastroenterology. 2021;161(6):1887-1895.e4. https://doi.org/10.1053/j.gastro.2021.08.050 . - DOI - PubMed
    1. Mah JM, DeWit Y, Djerboua M, Menard A, Booth CM, Flemming JA. Association between institutional factors and long-term survival following transjugular intrahepatic portosystemic shunt. JAMA Netw Open. 2019;3(6):838–46. https://doi.org/10.1002/HEP4.1345 . - DOI

Publication types

LinkOut - more resources