Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2025 Aug 18:18:1053-1056.
doi: 10.2147/IMCRJ.S520496. eCollection 2025.

Marcus-Gunn Jaw-Winking Phenomenon: A Case Report on Rare Oculofacial Synkinesis

Affiliations
Case Reports

Marcus-Gunn Jaw-Winking Phenomenon: A Case Report on Rare Oculofacial Synkinesis

Amjad Fiusal H Alharthe et al. Int Med Case Rep J. .

Abstract

The Marcus-Gunn jaw-winking phenomenon (MGJWP) is an uncommon congenital oculofacial synkinesis resulting from abnormal innervation between the fifth cranial nerve (trigeminal, CN V) and the third cranial nerve (oculomotor, CN III). This case report presents a 5-month-old girl with characteristic left eyelid elevation during suckling movements, highlighting the importance of clinical observation in early diagnosis. The condition was confirmed based on clinical findings, with no associated neurological or structural abnormalities. Management involved observation and follow-up to monitor potential complications such as strabismus or anisometropia. MGJWP remains an essential consideration in cases of unusual eyelid movement, emphasizing the role of multidisciplinary consultation for comprehensive care.

Keywords: Marcus-Gunn jaw-winking phenomenon; congenital synkinesis; eyelid movement; oculomotor nerve; trigeminal nerve.

PubMed Disclaimer

Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Showing involuntary movement of left eyelid while sucking.

Similar articles

References

    1. Alam MS, Nishanth S, Ramasubramanian S, Swaminathan M, Mukherjee B. The rare phenomenon of Marcus-Gunn jaw winking without ptosis: report of 14 cases and review of the literature. Indian J Ophthalmol. 2020;68(6):1132–1135. doi: 10.4103/ijo.IJO_1099_19 - DOI - PMC - PubMed
    1. Sano K. Trigemino-oculomotor synkinesis. Neurology. 1959;9(5):332–335.
    1. Barreira C, Barreira R. Marcus Gunn syndrome in primary care: a case report. Cureus. 2023;15(8):e43738. doi: 10.7759/cureus.43738 - DOI - PMC - PubMed
    1. Ziga N, Biscevic A, Pjano MA, Pidro A. Marcus Gunn Jaw-Winking syndrome: a case report. Med arch. 2019;73(4):282–284. doi: 10.5455/medarh.2019.73.282-284 - DOI - PMC - PubMed
    1. Pandey M, Baduni N, Jain A, Sanwal MK, Vajifdar H. Abnormal oculocardiac reflex in two patients with Marcus Gunn syndrome. J Anaesthesiol Clin Pharmacol. 2011;27(3):398–399. doi: 10.4103/0970-9185.83693 - DOI - PMC - PubMed

Publication types

LinkOut - more resources