68Ga-MY6349 PET/CT-guided TROP2-targeted therapy in mCRPC
- PMID: 40864221
- DOI: 10.1007/s00259-025-07501-x
68Ga-MY6349 PET/CT-guided TROP2-targeted therapy in mCRPC
Keywords: Metastatic castration-resistant prostate cancer; PET/CT imaging; TROP2-targeted therapy.
Conflict of interest statement
Declarations. Ethics approval: This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of Fudan University Shanghai Cancer Center. Consent to participate: The written informed consent for publication was obtained from the patients. Consent to publish: The authors affirm that human research participants provided informed consent for publication of the images in Fig. Competing interests: The authors declare no potential conflicts of interest.
References
-
- Yin Y, Fan Y, Ouyang Q, et al. Sacituzumabtirumotecan in previously treated metastatic triple-negative breast cancer: a randomized phase 3 trial. Nat Med. 2025. https://doi.org/10.1038/s41591-025-03630-w . - DOI - PubMed
-
- Chen H, Zhao L, Pang Y, et al. 68Ga-MY6349 PET/CT imaging to assess Trop2 expression in multiple types of cancer. J Clin Invest. 2024. https://doi.org/10.1172/JCI185408 . - DOI - PubMed - PMC
-
- Bardia A, Jhaveri K, Im S-A, et al. Datopotamab deruxtecan versus chemotherapy in previously treated inoperable/metastatic hormone receptor-positive human epidermal growth factor receptor 2–negative breast cancer: primary results from TROPION-Breast01. J Clin Oncol. 2025;43(3):285–96. - PubMed
Grants and funding
- 82473381/Innovative Research Group Project of the National Natural Science Foundation of China
- 82172621/Innovative Research Group Project of the National Natural Science Foundation of China
- 81972375/Innovative Research Group Project of the National Natural Science Foundation of China
- TP2022051/Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning
- 23XD1420600/Program of Shanghai Academic Research Leader
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