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. 2025 Aug 27.
doi: 10.1007/s13760-025-02875-z. Online ahead of print.

The prevalence of restless legs syndrome among university students: a single-centre study

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The prevalence of restless legs syndrome among university students: a single-centre study

Burhanettin Çiğdem et al. Acta Neurol Belg. .

Abstract

Introduction: Restless legs syndrome (RLS) is a relatively common movement disorder. Epidemiological data on RLS in young adults remain lacking. The objective of the present study was to determine the prevalence of primer RLS among university students comprising young adults.

Methods: The study was performed by two neurologists using the face-to-face survey method. A total of 3,047 students were included in the study. First, secondary causes of RLS were excluded by anamnesis. Then, eligible participants were asked to provide demographic data and answer five questions from the 2014 revised international restless legs syndrome study group (IRLSSG) diagnostic criteria; students who answered "yes" to the five questions were considered to have RLS and were invited to the hospital to further exclude secondary causes of RLS using medical data system, neurological examination, and blood tests. The IRLSSG severity scale was applied to measure the severity of the disease.

Results: Primary RLS was detected in 78 students comprising 44 females and 34 males, with a prevalence rate of 2.6%. Sleep disorders were more common in individuals with RLS (p = 0.005), and included difficulty falling asleep and waking up frequently (p = 0.001). Of the 78 students with RLS, 32 had first-degree relatives with RLS (41.02%).

Conclusion: When the secondary causes of RLS, which adversely affects the quality of life, is excluded, the prevalence of primary RLS in among included university students was 2.6%.

Keywords: Movement disorder; Prevalence; Restless legs syndrome; University students.

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Conflict of interest statement

Declarations. Competing interests: The authors have no financial or non-financial interests directly or indirectly related to this work submitted for publication.

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References

    1. Allen RP, Picchietti DL, Garcia-Borreguero D et al (2014) Restless legs syndrome/Willis-Ekbom disease diagnostic criteria: updated international restless legs syndrome study group (IRLSSG) consensus criteria–history, rationale, description, and significance. Sleep Med 15(8):860–873. https://doi.org/10.1016/j.sleep.2014.03.025 - DOI - PubMed
    1. Silber MH, Buchfuhrer MJ, Earley CJ et al (2021) The management of restless legs syndrome: an updated algorithm. Mayo Clin Proc 96(7):1921–1937. https://doi.org/10.1016/j.mayocp.2020.12.026 - DOI - PubMed
    1. Allen RP (2015) Restless leg syndrome/willis-ekbom disease pathophysiology. Sleep Med Clin 10(3):207–14. https://doi.org/10.1016/j.jsmc.2015.05.022 - DOI - PubMed - PMC
    1. Yeh P, Walters AS, Tsuang JW (2012) Restless legs syndrome: a comprehensive overview on its epidemiology, risk factors, and treatment. Sleep Breath 16(4):987–1007. https://doi.org/10.1007/s11325-011-0606-x - DOI - PubMed
    1. Allen RP, Walters AS, Montplaisir J et al (2005) Restless legs syndrome prevalence and impact: REST general population study. Arch Intern Med 165:1286–1292 - PubMed

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